Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.55 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18985254 | 1.00 | MEN1 (0.57) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL19003258 | 0.84 | TRPV1 (0.61) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL19003459 | 0.84 | CXCR1 (0.51) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL18985289 | 0.81 | MAOB (0.64) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL23547197 | 0.81 | TRPV1 (0.73) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL6754380 | 0.81 | TRPV1 (0.73) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL6754378 | 0.81 | TRPV1 (0.73) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL19003468 | 0.81 | ALDH1A1 (0.62) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL19003314 | 0.79 | MAOB (0.53) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL19003456 | 0.78 | MAPT (0.48) | MEN1KMT2AMAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | claimed |
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |