Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CISD2 | Q8N5K1 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867539 | 1.00 | LMNA (0.41) | LMNATSHRNPSR1CISD2CYP3A4 | |
| SCHEMBL25104302 | 0.87 | LMNA (0.41) | LMNATSHRNPSR1CISD2CYP3A4 | |
| SCHEMBL8116715 | 0.85 | CYP3A4 (0.40) | LMNATSHRCISD2CYP3A4ACHE | |
| SCHEMBL30798376 | 0.83 | SOS1 (0.40) | LMNATSHRNPSR1CYP3A4ACHE | |
| SCHEMBL24718692 | 0.83 | SOS1 (0.40) | LMNATSHRNPSR1CYP3A4ACHE | |
| SCHEMBL18786779 | 0.83 | CYP3A4 (0.46) | CISD2CYP3A4ACHEGRM6GRM5 | |
| SCHEMBL24649335 | 0.82 | SOS1 (0.39) | LMNATSHRNPSR1CYP3A4ACHE | |
| SCHEMBL30427242 | 0.82 | SOS1 (0.39) | LMNATSHRNPSR1CYP3A4ACHE | |
| SCHEMBL31024678 | 0.82 | LMNA (0.42) | LMNATSHRNPSR1CYP3A4ACHE | |
| SCHEMBL31426608 | 0.81 | CA1 (0.37) | CYP3A4ACHEKDM4EHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583867-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | Latigo Biotherapeutics, Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| CN-119894509-A | Sodium channel blocking compounds, derivatives thereof, and methods of use thereof | 拉堤果生物医疗股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024054622-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
| US-10779540-B2 | Benzamide compounds and their use as herbicides | BASF SE (DE) | 2020-09-22 | — | — | US | disclosed |
| EP-3390372-B1 | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2020-06-03 | — | — | EP | disclosed |
| EP-3390372-B1 | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2020-06-03 | — | — | EP | disclosed |
| US-20180360046-A1 | Benzamide Compounds and Their Use as Herbicides | BASF SE (DE) | 2018-12-20 | — | — | US | disclosed |
| EP-3390372-A1 | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2018-10-24 | — | — | EP | disclosed |
| WO-2017102275-A1 | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2017-06-22 | — | — | WO | disclosed |
| WO-2017102275-A1 | BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2017-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10779540-B2 | Benzamide compounds and their use as herbicides | DDT, DNPH1, BBOX1 | LMNA 3595/4885TSHR 2289/4885NPSR1 2240/4885 |
| US-20180360046-A1 | Benzamide Compounds and Their Use as Herbicides | DDT, DNPH1, BBOX1 | LMNA 3595/4885TSHR 2289/4885NPSR1 2240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.