Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18985307 | 0.74 | GAA (0.56) | PIN1TDP1KDM4EGAAMAPT | |
| SCHEMBL11107022 | 0.65 | HDAC1 (0.45) | PIN1KDM4EMAPT | |
| SCHEMBL29205065 | 0.63 | NAPRT (0.41) | TDP1KDM4EGAAMAPT | |
| SCHEMBL2282162 | 0.62 | KMT2A (0.53) | PIN1 | |
| SCHEMBL24687419 | 0.62 | HDAC6 (0.44) | PIN1DAOTSHRTDP1 | |
| SCHEMBL11304284 | 0.62 | PIN1 (0.36) | PIN1DAOALOX15TSHRCYP2C19 | |
| Hydrochloric Acid SCHEMBL1372985 | 0.61 | KMT2A (0.51) | PIN1MAPT | |
| SCHEMBL519233 | 0.60 | ALDH1A1 (0.39) | CYP2C19HIF1AKDM4EGAAMAPT | |
| SCHEMBL15108901 | 0.60 | KMT2A (0.58) | TSHRGAA | |
| SCHEMBL15782805 | 0.60 | CA12 (0.44) | DAOKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390363-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2018-10-24 | — | — | EP | disclosed |
| WO-2017102349-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2017-06-22 | — | — | WO | disclosed |