Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37979 | 0.94 | — | — | |
| Butane SCHEMBL7009352 | 0.84 | FDPS (0.42) | LAP3TDP1 | |
| SCHEMBL2991777 | 0.77 | — | — | |
| SCHEMBL3739812 | 0.74 | — | — | |
| SCHEMBL19695324 | 0.72 | — | — | |
| SCHEMBL1314077 | 0.72 | TP53 (0.38) | LAP3TP53SLC7A5 | |
| SCHEMBL319388 | 0.71 | — | — | |
| SCHEMBL9000959 | 0.71 | TP53 (0.42) | TP53SLC7A5 | |
| Bicarbonate SCHEMBL11206442 | 0.69 | LAP3 (0.43) | LAP3TP53TDP1 | |
| Phosphoric Acid SCHEMBL28196139 | 0.69 | TP53 (0.47) | LAP3TP53SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017100849-A1 | 6-OXOPURINE PHOSPHORIBOSYL TRANSFERASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-06-22 | — | — | WO | disclosed |