Butane

Butane

SCHEMBL7009352

CC(C(=O)O)P(=O)(O)O.CCCC

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FDPS P14324 4/20 0.42
METAP1 P53582 2/20 0.40
CHRM1 P11229 1/20 0.39
AKR1A1 P14550 1/20 0.39
CHRM3 P20309 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
ADRA1A P35348 1/20 0.39
HRH1 P35367 1/20 0.39
DRD3 P35462 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
FNTA P49354 1/20 0.38
FNTB P49356 1/20 0.38
LAP3 P28838 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37979 0.89
SCHEMBL18985285 0.84 LAP3 (0.42) TDP1LAP3
Fosfonet SCHEMBL7452888 0.80 MEN1 (0.45) HDAC1HDAC2TDP1
Butane SCHEMBL10388720 0.78 METAP1 (0.43) FDPSMETAP1TDP1LAP3
SCHEMBL1313868 0.76 CHRM1 (0.36) FDPSCHRM1AKR1A1CHRM3HTR2A
SCHEMBL1313336 0.75 ANPEP (0.37) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL2990965 0.73 CHRM1 (0.37) CHRM1AKR1A1CHRM3HTR2AHTR2C
Butane SCHEMBL7718918 0.73 FOLH1 (0.50) FDPSMETAP1CHRM1AKR1A1CHRM3
Butane SCHEMBL7717037 0.73 FNTA (0.41) FDPSMETAP1FNTAFNTB
SCHEMBL1315919 0.73 TRPM8 (0.42) FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118667136-A Ti-Mg bimetallic titanium catalyst and preparation method and application thereof 山东道恩降解材料有限公司 2024-09-20 CN claimed
CN-118055670-A Green solvent of perovskite solar cell perovskite light absorption layer and preparation method of perovskite solar cell 西北工业大学 2024-05-17 CN claimed
CN-115045001-B High-melting-point PBAT copolyester fiber and preparation method thereof 万华化学集团股份有限公司 2024-05-03 CN claimed
CN-115045001-A High-melting-point PBAT copolyester fiber and preparation method thereof 万华化学集团股份有限公司 2022-09-13 CN claimed
CN-112280011-B Preparation method of low-melting-index poly (butylene succinate) 康辉新材料科技有限公司 2022-08-05 CN claimed
CN-112266471-B Preparation method of polybutylene adipate-terephthalate 康辉新材料科技有限公司 2022-08-05 CN claimed
CN-112390940-B Catalyst for polyester synthesis 康辉新材料科技有限公司 2022-08-05 CN claimed
CN-113512182-A PBS (Poly Butylene succinate) resin composition and preparation method thereof 万华化学集团股份有限公司 2021-10-19 CN claimed
CN-112280012-B Preparation method of poly (butylene succinate) 康辉新材料科技有限公司 2021-09-07 CN claimed
CN-112390940-A Catalyst for polyester synthesis 营口康辉石化有限公司 2021-02-23 CN claimed
CN-112280011-A Preparation method of low-melting-index poly (butylene succinate) 营口康辉石化有限公司 2021-01-29 CN claimed
CN-112280012-A Preparation method of poly (butylene succinate) 营口康辉石化有限公司 2021-01-29 CN claimed
CN-112266471-A Preparation method of polybutylene adipate-terephthalate 营口康辉石化有限公司 2021-01-26 CN claimed
CN-119255683-A Preparation process of perovskite layer and perovskite solar cell 链行走新材料科技(广州)有限公司 2025-01-03 CN disclosed
CN-118667136-A Ti-Mg bimetallic titanium catalyst and preparation method and application thereof 山东道恩降解材料有限公司 2024-09-20 CN disclosed
CN-118055670-A Green solvent of perovskite solar cell perovskite light absorption layer and preparation method of perovskite solar cell 西北工业大学 2024-05-17 CN disclosed
US-5059610-A QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1991-10-22 US disclosed
US-4920132-A Quinoline derivatives and use thereof as antagonists of leukotriene D4 RORER PHARMACEUTICAL CORP. (US) 1990-04-24 US disclosed
WO-1989004305-A1 QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 RORER INTERNATIONAL (OVERSEAS) INC. (US) 1989-05-18 WO disclosed
EP-0315399-A2 Quinoline derivatives, their use in the treatment of hypersensitive ailments and a pharmaceutical composition containing the same RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1989-05-10 EP disclosed