Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.73 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.71 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18342948 | 0.98 | ALOX5 (0.74) | ALOX5PTGS2PTGESCYP1A2HTR2A | |
| SCHEMBL21558842 | 0.98 | ALOX5 (0.74) | ALOX5PTGS2PTGESCYP1A2HTR2A | |
| SCHEMBL29711563 | 0.98 | ALOX5 (0.74) | ALOX5PTGS2PTGESCYP1A2HTR2A | |
| SCHEMBL4902893 | 0.85 | ALOX5 (1.00) | ALOX5PTGS2HTR2ATDP1 | |
| SCHEMBL5270031 | 0.84 | ALOX5 (0.54) | ALOX5PTGS2PTGESCYP1A2TDP1 | |
| SCHEMBL15758094 | 0.82 | ALOX5 (0.71) | ALOX5PTGS2HTR2A | |
| SCHEMBL25554478 | 0.81 | ALOX5 (0.52) | ALOX5PTGS2PTGESCYP1A2HTR2A | |
| SCHEMBL22903657 | 0.80 | ALOX5 (0.51) | ALOX5PTGS2PTGESCYP1A2HTR2A | |
| SCHEMBL28605004 | 0.79 | ALOX5 (0.54) | ALOX5PTGS2PTGESCYP1A2TDP1 | |
| SCHEMBL28274331 | 0.79 | CALM1 (0.46) | ALOX5PTGS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210228535-A1 | SMALL MOLECULES AGAINST CANCER | BIOKINE THERAPEUTICS LTD. (IL) | 2021-07-29 | — | — | US | disclosed |
| US-10959979-B2 | Small molecules against cancer | BIOKINE THERAPEUTICS LTD. (IL) | 2021-03-30 | — | — | US | disclosed |
| US-20200268709-A1 | SMALL MOLECULES AGAINST CANCER | BIOKINE THERAPEUTICS LTD. (IL) | 2020-08-27 | — | — | US | disclosed |
| US-10646465-B2 | Small molecules against cancer | BIOKINE THERAPEUTICS LTD. (IL) | 2020-05-12 | — | — | US | disclosed |
| US-20190240188-A1 | SMALL MOLECULES AGAINST CANCER | ALONBIO LTD. (IL) | 2019-08-08 | — | — | US | disclosed |
| EP-3390378-A1 | SMALL MOLECULES AGAINST CANCER | Biokine Therapeutics Ltd. (IL) | 2018-10-24 | — | — | EP | disclosed |
| WO-2017103931-A1 | SMALL MOLECULES AGAINST CANCER | BIOKINE THERAPEUTICS LTD. (IL) | 2017-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10959979-B2 | Small molecules against cancer | CCL2, CXCR2, CCL5 | ALOX5 2004/4885PTGS2 382/4885PTGES 358/4885 |
| US-20210228535-A1 | SMALL MOLECULES AGAINST CANCER | CCL2, CXCR2, CCL5 | ALOX5 2004/4885PTGS2 382/4885PTGES 358/4885 |
| US-10646465-B2 | Small molecules against cancer | CCL2, CXCR2, CCL5 | ALOX5 2004/4885PTGS2 382/4885PTGES 358/4885 |
| US-20200268709-A1 | SMALL MOLECULES AGAINST CANCER | CCL2, CXCR2, CCL5 | ALOX5 2004/4885PTGS2 382/4885PTGES 358/4885 |
| US-20190240188-A1 | SMALL MOLECULES AGAINST CANCER | CCL2, CXCR2, CCL5 | ALOX5 2004/4885PTGS2 382/4885PTGES 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.