Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ARG1 | P05089 | 3/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10495130 | 0.80 | THRB (0.48) | THRBTSHRALDH1A1APEX1POLB | |
| Hydrochloric Acid SCHEMBL5538296 | 0.79 | THRB (0.47) | THRBTSHRALDH1A1APEX1POLB | |
| SCHEMBL11330737 | 0.78 | THRB (0.50) | THRBTSHRALDH1A1APEX1POLB | |
| SCHEMBL7625934 | 0.77 | THRB (0.48) | THRBTSHRALDH1A1APEX1POLB | |
| SCHEMBL26979799 | 0.77 | THRB (0.48) | THRBTSHRALDH1A1APEX1POLB | |
| SCHEMBL18492454 | 0.77 | THRB (0.48) | THRBTSHRALDH1A1APEX1POLB | |
| SCHEMBL26002227 | 0.75 | THRB (0.55) | THRBTSHRALDH1A1APEX1POLB | |
| Ammonia Solution, Strong SCHEMBL19133680 | 0.75 | THRB (0.47) | THRBTSHRALDH1A1APEX1POLB | |
| Methacrylic Acid SCHEMBL28665407 | 0.75 | THRB (0.47) | THRBTSHRALDH1A1APEX1POLB | |
| SCHEMBL15194578 | 0.75 | THRB (0.47) | THRBTSHRALDH1A1APEX1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738780-B2 | Crosslinked mixed charge hydrogels | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-08-22 | — | — | US | disclosed |
| US-20170009069-A1 | CROSSLINKED ZWITTERIONIC HYDROGELS | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-01-12 | — | — | US | disclosed |
| US-9394435-B2 | Crosslinked zwitterionic hydrogels | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2016-07-19 | — | — | US | disclosed |
| EP-2496550-B1 | CROSSLINKED ZWITTERIONIC HYDROGELS | UNIV WASHINGTON CT COMMERCIALI (US) | 2015-08-05 | — | — | EP | disclosed |
| US-20150037598-A1 | CROSSLINKED ZWITTERIONIC HYDROGELS | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2015-02-05 | — | — | US | disclosed |
| US-8835671-B2 | Crosslinked zwitterionic hydrogels | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120322939-A1 | CROSSLINKED ZWITTERIONIC HYDROGELS | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2012-12-20 | — | — | US | disclosed |
| EP-2496550-A2 | CROSSLINKED ZWITTERIONIC HYDROGELS | University Of Washington Through Its Center For Commercialization (US) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011057219-A2 | CROSSLINKED ZWITTERIONIC HYDROGELS | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2011-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322939-A1 | CROSSLINKED ZWITTERIONIC HYDROGELS | ZW10, MTCL3, PHOSPHO1 | THRB 4589/4885TSHR 4303/4885ALDH1A1 3008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.