Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761016 | 0.84 | MAPT (0.43) | LMNAPOLBSMN1; SMN2MAPTGBA2 | |
| SCHEMBL14144107 | 0.82 | POLB (0.45) | LMNAPOLBSMN1; SMN2MAPTGBA2 | |
| SCHEMBL5250880 | 0.81 | POLB (0.44) | LMNAPOLBSMN1; SMN2MAPTGBA2 | |
| SCHEMBL3982504 | 0.81 | POLB (0.53) | LMNAPOLBSMN1; SMN2MAPTGBA2 | |
| SCHEMBL1982237 | 0.81 | POLB (0.53) | LMNAPOLBSMN1; SMN2MAPTGBA2 | |
| SCHEMBL6207733 | 0.81 | POLB (0.53) | LMNAPOLBSMN1; SMN2MAPTGBA2 | |
| SCHEMBL5250883 | 0.81 | POLB (0.44) | LMNAPOLBSMN1; SMN2MAPTGBA2 | |
| SCHEMBL27400845 | 0.81 | ALDH1A1 (0.38) | LMNAPOLBSMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL6119301 | 0.80 | MAPT (0.43) | LMNAPOLBSMN1; SMN2MAPTGBA2 | |
| SCHEMBL7563929 | 0.80 | POLB (0.43) | LMNAPOLBSMN1; SMN2MAPTGBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390421-A1 | METAL COMPLEXES | University of Leeds (GB) | 2018-10-24 | — | — | EP | disclosed |
| WO-2017103623-A1 | METAL COMPLEXES | UNIVERSITY OF LEEDS (GB) | 2017-06-22 | — | — | WO | disclosed |