Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.40 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6119301 | 0.88 | MAPT (0.43) | MAPTLMNAPOLBSMN1; SMN2FKBP1A | |
| SCHEMBL6336988 | 0.86 | MAPT (0.43) | MAPTLMNAPOLBSMN1; SMN2FKBP1A | |
| SCHEMBL31648060 | 0.86 | MAPT (0.43) | MAPTLMNAPOLBSMN1; SMN2FKBP1A | |
| SCHEMBL2913340 | 0.85 | POLB (0.47) | MAPTALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL14144107 | 0.84 | POLB (0.45) | MAPTALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL18987370 | 0.84 | LMNA (0.39) | MAPTLMNAPOLBSMN1; SMN2FKBP1A | |
| SCHEMBL3036913 | 0.83 | LMNA (0.42) | MAPTLMNAPOLBSMN1; SMN2GBA2 | |
| SCHEMBL6207733 | 0.83 | POLB (0.53) | MAPTALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL1982237 | 0.83 | POLB (0.53) | MAPTALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL5250880 | 0.83 | POLB (0.44) | MAPTALDH1A1LMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289842-B1 | REMEDY AGAINST INSECTS AND MITES | BAYER AG (DE) | 1991-11-27 | — | — | EP | disclosed |
| US-5008261-A | Long-lasting | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-16 | — | — | US | disclosed |
| US-4900834-A | INSECT AND MITE REPELLENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-02-13 | — | — | US | disclosed |
| EP-0289842-A1 | Remedy against insects and mites | BAYER AG (DE) | 1988-11-09 | — | — | EP | disclosed |