Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.83 |
| ▸ | MEN1 | O00255 | 1/20 | 0.83 |
| ▸ | ABL1 | P00519 | 1/20 | 0.83 |
| ▸ | LMNA | P02545 | 1/20 | 0.83 |
| ▸ | PKM | P14618 | 1/20 | 0.83 |
| ▸ | IDE | P14735 | 1/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.83 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.83 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.83 |
| ▸ | HLCS | P50747 | 5/20 | 0.59 |
| ▸ | CA12 | O43570 | 8/20 | 0.56 |
| ▸ | CA1 | P00915 | 8/20 | 0.56 |
| ▸ | CA2 | P00918 | 8/20 | 0.56 |
| ▸ | CA9 | Q16790 | 8/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biotin SCHEMBL16540693 | 0.92 | TDP1 (0.77) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL23124079 | 0.92 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL723192 | 0.91 | TDP1 (0.90) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL4350764 | 0.91 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL21981206 | 0.91 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL20547409 | 0.91 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL14489489 | 0.91 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL22943835 | 0.91 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL23055065 | 0.91 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL38817 | 0.91 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018092-B2 | Covalent heterobivalent antibody inhibitors and ligands | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2024-06-25 | — | — | US | disclosed |
| US-20210115157-A1 | COVALENT HETEROBIVALENT ANTIBODY INHIBITORS AND LIGANDS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2021-04-22 | — | — | US | disclosed |
| US-10947320-B2 | Covalent heterobivalent antibody inhibitors and ligands | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2021-03-16 | — | — | US | disclosed |
| WO-2017106859-A1 | COVALENT HETEROBIVALENT ANTIBODY INHIBITORS AND LIGANDS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2017-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12018092-B2 | Covalent heterobivalent antibody inhibitors and ligands | BTD, DBI, FCER2 | TDP1 4308/4885MEN1 3537/4885ABL1 147/4885 |
| US-10947320-B2 | Covalent heterobivalent antibody inhibitors and ligands | BTD, DBI, FCER2 | TDP1 4308/4885MEN1 3537/4885ABL1 147/4885 |
| US-20210115157-A1 | COVALENT HETEROBIVALENT ANTIBODY INHIBITORS AND LIGANDS | BTD, DBI, FCER2 | TDP1 4308/4885MEN1 3537/4885ABL1 147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.