Biotin

Biotin

SCHEMBL14489489

O=C(O)CCCC[C@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 6/20 1.00
▸ MEN1 O00255 1/20 1.00
▸ ABL1 P00519 1/20 1.00
▸ LMNA P02545 1/20 1.00
▸ PKM P14618 1/20 1.00
▸ IDE P14735 1/20 1.00
▸ MAPK1 P28482 1/20 1.00
▸ KMT2A Q03164 1/20 1.00
▸ RIN1 Q13671 1/20 1.00
▸ L3MBTL1 Q9Y468 1/20 1.00
▸ HLCS P50747 6/20 0.69
▸ CA12 O43570 7/20 0.56
▸ CA1 P00915 7/20 0.56
▸ CA2 P00918 7/20 0.56
▸ CA9 Q16790 7/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biotin SCHEMBL13272362 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL10047687 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL8763 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL38817 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL16897730 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL23055065 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL21981206 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL20547409 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL22943835 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL5690544 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120138181-A Primer group for detecting mycoplasma pneumoniae and drug-resistant mutation thereof and application of primer group 常州市儿童医院(常州市第六人民医院) 2025-06-13 — — CN claimed
EP-4416303-A1 A MICROSPHERE COMPRISING A FIRST MATERIAL AND A SECOND MATERIAL Blink AG (DE) 2024-08-21 — — EP claimed
CN-118510909-A Microsphere comprising a first material and a second material 布林克公司 2024-08-16 — — CN claimed
EP-4317163-A1 METHOD FOR PREPARING BIOTIN, L-LYSINE SALT OF BIOTIN, AND METHOD FOR PREPARING SAME Tokuyama Corporation (JP) 2024-02-07 — — EP claimed
CN-117062820-A Method for producing biotin, and L-lysine salt of biotin and method for producing same 株式会社德山 2023-11-14 — — CN claimed
US-20230338553-A1 DELIVERY SYSTEM FOR TARGETED DELIVERY OF A THERAPEUTICALLY ACTIVE PAYLOAD Technische Universität Dresden (CH) 2023-10-26 — — US claimed
WO-2023169899-A1 TARGETED DELIVERY OF OLIGONUCLEOTIDES INTO EUKARYOTIC CELLS USING HYBRID MALTOSE/CYCLODEXTRIN POLYPLEXES TECHNISCHE UNIVERSITÄT DRESDEN E.V. (DE) 2023-09-14 — — WO claimed
EP-4238581-A1 TARGETED DELIVERY OF OLIGONUCLEOTIDES INTO EUKARYOTIC CELLS USING HYBRID MALTOSE/CYCLODEXTRIN POLYPLEXES Technische Universität Dresden e. V. (DE) 2023-09-06 — — EP claimed
WO-2023079140-A1 A MICROSPHERE COMPRISING A FIRST MATERIAL AND A SECOND MATERIAL BLINK AG (DE) 2023-05-11 — — WO claimed
EP-4177352-A1 A MICROSPHERE COMPRISING A FIRST MATERIAL AND A SECOND MATERIAL Blink AG (DE) 2023-05-10 — — EP claimed
US-20230126528-A1 A LIBRARY OF PREFABRICATED MICROPARTICLES AND PRECURSORS THEREOF BLINK AG (DE) 2023-04-27 — — US claimed
EP-4078180-A1 A LIBRARY OF PREFABRICATED MICROPARTICLES AND PRECURSORS THEREOF Blink AG (DE) 2022-10-26 — — EP claimed
CN-115176156-A Library of preformed microparticles and precursors thereof 布林克公司 2022-10-11 — — CN claimed
WO-2022202982-A1 METHOD FOR PREPARING BIOTIN, L-LYSINE SALT OF BIOTIN, AND METHOD FOR PREPARING SAME 株式会社トクヤマ 2022-09-29 — — WO claimed
CN-114540465-A RPA amplification method suitable for low abundance sample detection 中国疾病预防控制中心传染病预防控制所 2022-05-27 — — CN claimed
EP-3729090-B1 MODIFIED BIOTIN-BINDING PROTEINS FOR IMMOBILIZATION PACIFIC BIOSCIENCES CALIFORNIA INC (US) 2026-05-27 — — EP disclosed
EP-4727537-A2 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF Adaxion Therapeutics, Inc. (US) 2026-04-22 — — EP disclosed
US-20070141105-A1 Engineered Biological Matrices CAMBREX BIO SCIENCE WALKERSVILLE, INC. 2007-06-21 — — US disclosed
US-20070141105-A1 Engineered Biological Matrices CAMBREX BIO SCIENCE WALKERSVILLE, INC. 2007-06-21 — — US disclosed
WO-2007044669-A2 ENGINEERED BIOLOGICAL MATRICES LONZA WALKERSVILLE, INC. (US) 2007-04-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070141105-A1 Engineered Biological Matrices BMP2, HMGB1, BMP4 TDP1 2232/4885MEN1 4142/4885ABL1 1538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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