Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 8/20 | 0.48 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 2/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14822500 | 0.84 | P4HA1 (0.59) | HCAR3P4HA1P4HTMCNR2MIF | |
| SCHEMBL30590918 | 0.84 | P4HA1 (0.59) | HCAR3P4HA1P4HTMCNR2MIF | |
| SCHEMBL22562748 | 0.81 | HCAR3 (0.57) | HCAR3P4HA1P4HTMCNR2MIF | |
| SCHEMBL21905475 | 0.81 | HCAR3 (0.57) | HCAR3P4HA1P4HTMCNR2MIF | |
| SCHEMBL169296 | 0.77 | P4HA1 (0.50) | HCAR3P4HA1P4HTMCNR2HPGDS | |
| SCHEMBL17366211 | 0.76 | P4HA1 (0.49) | HCAR3P4HA1P4HTMCNR2MIF | |
| SCHEMBL21098093 | 0.73 | P4HA1 (0.53) | HCAR3P4HA1P4HTMMIFLDHA | |
| SCHEMBL18397093 | 0.73 | MEN1 (0.43) | HCAR3P4HA1P4HTMCNR2HPGDS | |
| SCHEMBL29539403 | 0.73 | MEN1 (0.43) | HCAR3P4HA1P4HTMCNR2HPGDS | |
| SCHEMBL16679112 | 0.72 | ABL1 (0.36) | HCAR3HPGDSESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682953-B2 | Amide compounds, compositions and applications thereof | ADVINUS THERAPEUTICS LIMITED (IN) | 2017-06-20 | — | — | US | disclosed |
| US-9682953-B2 | Amide compounds, compositions and applications thereof | ADVINUS THERAPEUTICS LIMITED (IN) | 2017-06-20 | — | — | US | disclosed |