SCHEMBL22562748

SCHEMBL22562748

O=C(O)c1ccc(C2CCC2)nc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 6/20 0.57
P4HA1 P13674 3/20 0.55
P4HTM Q9NXG6 2/20 0.55
MIF P14174 1/20 0.48
LDHA P00338 1/20 0.47
GABRP O00591 1/20 0.47
GABRD O14764 1/20 0.47
GABRA1 P14867 1/20 0.47
GABRB1 P18505 1/20 0.47
GABRG2 P18507 1/20 0.47
GABRB3 P28472 1/20 0.47
GABRA5 P31644 1/20 0.47
GABRA3 P34903 1/20 0.47
GABRA2 P47869 1/20 0.47
GABRB2 P47870 1/20 0.47
GABRA4 P48169 1/20 0.47
GABRE P78334 1/20 0.47
GABRA6 Q16445 1/20 0.47
GABRG1 Q8N1C3 1/20 0.47
GABRG3 Q99928 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21905475 0.96 HCAR3 (0.57) HCAR3P4HA1P4HTMMIFLDHA
SCHEMBL30590918 0.93 P4HA1 (0.59) HCAR3P4HA1P4HTMMIFLDHA
SCHEMBL14822500 0.93 P4HA1 (0.59) HCAR3P4HA1P4HTMMIFLDHA
SCHEMBL169296 0.85 P4HA1 (0.50) HCAR3P4HA1P4HTMMIFLDHA
SCHEMBL30521375 0.84 GLS (0.44) HCAR3P4HA1P4HTMALDH1A1CNR2
SCHEMBL25805056 0.84 GLS (0.44) HCAR3P4HA1P4HTMALDH1A1CNR2
SCHEMBL17366211 0.83 P4HA1 (0.49) HCAR3P4HA1P4HTMMIFLDHA
SCHEMBL171510 0.83 HCAR3 (0.48) HCAR3P4HA1P4HTM
SCHEMBL18993133 0.81 HCAR3 (0.48) HCAR3P4HA1P4HTMMIFLDHA
SCHEMBL21098093 0.81 P4HA1 (0.53) HCAR3P4HA1P4HTMMIFLDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4618978-A1 COMPOUNDS, COMPOSITIONS, AND METHODS Tenvie Therapeutics Inc. (US) 2025-09-24 EP disclosed
WO-2024108147-A1 COMPOUNDS, COMPOSITIONS, AND METHODS DENALI THERAPEUTICS INC. (US) 2024-05-23 WO disclosed
WO-2024108147-A1 COMPOUNDS, COMPOSITIONS, AND METHODS DENALI THERAPEUTICS INC. (US) 2024-05-23 WO disclosed
WO-2024074611-A1 PRMT5 INHIBITORS Ryvu Therapeutics S.A. (PL) 2024-04-11 WO disclosed
EP-3512486-B2 BLUE POWDER AND USE THEREOF IN COSMETICS OREAL (FR) 2023-07-12 EP disclosed
EP-3512486-B1 BLUE POWDER AND USE THEREOF IN COSMETICS OREAL (FR) 2020-10-21 EP disclosed