SCHEMBL18993255

SCHEMBL18993255

Cc1ccc(N(c2ccc(/C=C/C=C/c3ccc(C(C)(C)C)cc3)cc2)c2ccccc2C)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
APP P05067 1/20 0.36
CYP1A2 P05177 1/20 0.36
TRPV1 Q8NER1 2/20 0.35
HCRTR2 O43614 2/20 0.34
TRPM8 Q7Z2W7 2/20 0.34
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
NFE2L2 Q16236 2/20 0.33
RELA Q04206 1/20 0.32
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
MAPT P10636 1/20 0.31
TNIK Q9UKE5 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17551533 0.92 APP (0.36) NR1H2NR1H3APPCYP1A2TRPV1
SCHEMBL18993248 0.87 MAOB (0.44) APPTRPM8NFE2L2RELARAB9A
SCHEMBL13358327 0.86 NR1H2 (0.39) NR1H2NR1H3CYP1A2TRPV1RELA
SCHEMBL13358009 0.86 RELA (0.40) NR1H2NR1H3APPCYP1A2TRPV1
SCHEMBL4402146 0.84 RELA (0.44) APPTRPM8PTGS1PTGS2NFE2L2
SCHEMBL21173573 0.84 TSHR (0.41) TSHRRELANPC1RAB9AMAPT
SCHEMBL13358367 0.83 RELA (0.40) NR1H2NR1H3APPCYP1A2TRPV1
SCHEMBL13358103 0.83 RELA (0.37) NR1H2NR1H3APPCYP1A2TRPV1
SCHEMBL13358302 0.83 RELA (0.37) NR1H2NR1H3APPCYP1A2TRPV1
SCHEMBL13358471 0.83 RELA (0.37) NR1H2NR1H3APPCYP1A2TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9684253-B2 Triphenylamine derivative, electrophotographic photosensitive member, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-06-20 US disclosed
US-9684253-B2 Triphenylamine derivative, electrophotographic photosensitive member, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-06-20 US disclosed