SCHEMBL18993248

SCHEMBL18993248

Cc1ccc(N(c2ccc(/C=C/C=C/c3ccccc3)cc2)c2ccccc2C)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.44
RELA Q04206 1/20 0.43
TRPM8 Q7Z2W7 2/20 0.41
APP P05067 1/20 0.41
ALDH1A1 P00352 6/20 0.39
HTT P42858 1/20 0.39
CTDSP1 Q9GZU7 1/20 0.38
ALOX5 P09917 1/20 0.37
MAPT P10636 4/20 0.37
CYP1B1 Q16678 1/20 0.37
CYP3A4 P08684 1/20 0.37
HPGD P15428 1/20 0.37
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
GAA P10253 3/20 0.37
KDM4E B2RXH2 2/20 0.37
PKM P14618 2/20 0.36
NFE2L2 Q16236 2/20 0.36
MAPK1 P28482 3/20 0.35
PLIN1 O60240 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13239567 0.95 MAOB (0.48) MAOBRELAAPPALDH1A1HTT
SCHEMBL15759524 0.94 APP (0.47) MAOBRELAAPPALDH1A1HTT
SCHEMBL17549420 0.91 MAOB (0.44) MAOBRELAAPPALDH1A1HTT
SCHEMBL4402146 0.90 RELA (0.44) RELATRPM8APPALDH1A1CTDSP1
SCHEMBL13372131 0.89 TRPM8 (0.45) RELATRPM8APPALDH1A1CTDSP1
SCHEMBL13358253 0.89 TRPM8 (0.45) RELATRPM8APPALDH1A1CTDSP1
SCHEMBL18417178 0.89 RELA (0.55) MAOBRELAAPPALDH1A1CTDSP1
SCHEMBL18993254 0.88 NFE2L2 (0.41) MAOBRELATRPM8APPALDH1A1
SCHEMBL18993255 0.87 TSHR (0.41) RELATRPM8APPMAPTMEN1
SCHEMBL14526484 0.87 RELA (0.44) RELATRPM8APPALDH1A1CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9684253-B2 Triphenylamine derivative, electrophotographic photosensitive member, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-06-20 US disclosed
US-9684253-B2 Triphenylamine derivative, electrophotographic photosensitive member, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-06-20 US disclosed