SCHEMBL4402146

SCHEMBL4402146

Cc1ccc(N(c2ccc(C=Cc3ccc(C=Cc4ccc(N(c5ccc(C)cc5)c5ccccc5C)cc4)cc3)cc2)c2ccccc2C)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 2/20 0.44
NFE2L2 Q16236 5/20 0.43
ALOX5 P09917 1/20 0.42
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
TRPM8 Q7Z2W7 2/20 0.41
FGF23 Q9GZV9 1/20 0.40
CTDSP1 Q9GZU7 1/20 0.39
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
INSR P06213 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP3A4 P08684 1/20 0.38
TP53 P04637 1/20 0.37
RAB9A P51151 3/20 0.37
MEN1 O00255 2/20 0.37
APOBEC3A P31941 2/20 0.37
KMT2A Q03164 2/20 0.37
APOBEC3G Q9HC16 2/20 0.37
APP P05067 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14526484 0.96 RELA (0.44) RELANFE2L2ALOX5PTGS1PTGS2
SCHEMBL13358253 0.95 TRPM8 (0.45) RELANFE2L2ALOX5PTGS1PTGS2
SCHEMBL19422632 0.95 RELA (0.41) RELANFE2L2ALOX5PTGS1PTGS2
SCHEMBL13372131 0.95 TRPM8 (0.45) RELANFE2L2ALOX5PTGS1PTGS2
SCHEMBL4923203 0.95 RELA (0.43) RELANFE2L2ALOX5PTGS1PTGS2
SCHEMBL13308471 0.94 NFE2L2 (0.50) RELANFE2L2ALOX5PTGS1PTGS2
SCHEMBL13308461 0.92 NFE2L2 (0.49) RELANFE2L2ALOX5PTGS1PTGS2
SCHEMBL13358439 0.92 TRPM8 (0.45) RELANFE2L2ALOX5PTGS1PTGS2
SCHEMBL18417178 0.91 RELA (0.55) RELANFE2L2ALOX5PTGS1PTGS2
SCHEMBL13358626 0.91 TRPM8 (0.42) RELANFE2L2ALOX5PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-20130022902-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-01-24 US disclosed
US-20130022902-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-01-24 US disclosed
US-20120321348-A1 IMAGE BEARING DRUM, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2012-12-20 US disclosed
US-20120321348-A1 IMAGE BEARING DRUM, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2012-12-20 US disclosed
US-8273513-B2 Image forming apparatus, process cartridge, and image bearing member RICOH COMPANY, LIMITED (JP) 2012-09-25 US disclosed
US-8273513-B2 Image forming apparatus, process cartridge, and image bearing member RICOH COMPANY, LIMITED (JP) 2012-09-25 US disclosed
US-8178266-B2 Electrophotographic photoreceptor, image forming apparatus using the electrophotographic photoreceptor, and method of producing electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-20090324281-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2009-12-31 US disclosed
EP-2138899-A1 Electrophotographic photoreceptor, image forming apparatus using the electrophotographic photoreceptor, and method of producing electrophotographic photoreceptor Ricoh Company, Limited (JP) 2009-12-30 EP disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
US-20080292981-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS USING THE SAME RICOH COMPANY LIMITED (JP) 2008-11-27 US disclosed
US-20080292981-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS USING THE SAME RICOH COMPANY LIMITED (JP) 2008-11-27 US disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed