Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 15/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18027789 | 0.86 | RAB9A (0.55) | S1PR1S1PR3 | |
| SCHEMBL18010126 | 0.82 | S1PR1 (0.44) | S1PR1S1PR3KMOGRM4EGFR | |
| SCHEMBL18993450 | 0.79 | GRM4 (0.63) | S1PR1GRM4 | |
| SCHEMBL16692701 | 0.75 | NFKB1 (0.39) | — | |
| SCHEMBL2880086 | 0.74 | S1PR1 (0.58) | S1PR1S1PR3KMOGRM4 | |
| SCHEMBL18993386 | 0.74 | POLB (0.57) | GRM4 | |
| SCHEMBL18993402 | 0.73 | NPC1 (0.65) | GRM4 | |
| SCHEMBL24892340 | 0.71 | S1PR1 (0.68) | S1PR1S1PR3 | |
| SCHEMBL18993441 | 0.71 | F2R (0.51) | GRM4 | |
| SCHEMBL18993406 | 0.71 | NPC1 (0.72) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682931-B2 | Aryloyl(oxy or amino)pentafluorosulfanylbenzene compound, pharmaceutically acceptable salt thereof, and prodrugs thereof | UBE INDUSTRIES, LTD. (JP) | 2017-06-20 | — | — | US | disclosed |