Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | SELL | P14151 | 1/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | TOP1 | P11387 | 2/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18027773 | 0.83 | NPC1 (0.63) | TERTLMNAALOX15MEN1TP53 | |
| SCHEMBL9051568 | 0.82 | MEN1 (0.65) | TERTSELLSELPLMNAMEN1 | |
| SCHEMBL18010077 | 0.79 | TERT (0.47) | TERTP2RX1SELLSELPLMNA | |
| SCHEMBL24823417 | 0.79 | P2RX1 (0.63) | P2RX1LMNATP53HTTNPC1 | |
| SCHEMBL22851939 | 0.78 | TERT (0.79) | TERTLMNAALOX15MEN1TP53 | |
| SCHEMBL24824703 | 0.75 | EPHX2 (0.58) | P2RX1MEN1KMT2AHPGDNPC1 | |
| SCHEMBL15313832 | 0.74 | BCL2L1 (0.63) | P2RX1LMNAALOX15MEN1KMT2A | |
| SCHEMBL27736254 | 0.74 | LMNA (0.74) | TERTLMNAMEN1TP53HTT | |
| SCHEMBL18993415 | 0.74 | TOP1 (0.82) | LMNATOP1TOP2ATOP2BHTT | |
| SCHEMBL2169634 | 0.74 | MEN1 (0.68) | TERTLMNAMEN1TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682931-B2 | Aryloyl(oxy or amino)pentafluorosulfanylbenzene compound, pharmaceutically acceptable salt thereof, and prodrugs thereof | UBE INDUSTRIES, LTD. (JP) | 2017-06-20 | — | — | US | disclosed |