Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18133177 | 0.77 | P2RX7 (0.38) | P2RX7ALDH1A1FGF23MKNK1MKNK2 | |
| SCHEMBL935465 | 0.77 | — | — | |
| SCHEMBL20131035 | 0.76 | P2RX7 (0.36) | P2RX7MKNK1MKNK2TRIM24TRIM33 | |
| Hydrochloric Acid SCHEMBL4201170 | 0.75 | ALDH1A1 (0.37) | P2RX7ALDH1A1FGF23MKNK1MKNK2 | |
| SCHEMBL21094709 | 0.74 | P2RX7 (0.37) | P2RX7ALDH1A1FGF23MKNK1MKNK2 | |
| SCHEMBL11173012 | 0.73 | TRIM24 (0.35) | P2RX7ALDH1A1FGF23MKNK1MKNK2 | |
| SCHEMBL14677805 | 0.72 | — | — | |
| SCHEMBL14885546 | 0.72 | TDP1 (0.36) | P2RX7ALDH1A1MKNK1MKNK2L3MBTL1 | |
| SCHEMBL9117952 | 0.71 | CA1 (0.50) | P2RX7ALDH1A1 | |
| SCHEMBL22199160 | 0.71 | P2RX7 (0.41) | P2RX7ALDH1A1FGF23MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682960-B2 | Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety | ENDORECHERCHE, INC. (CA) | 2017-06-20 | — | — | US | disclosed |