Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | F13A1 | P00488 | 1/20 | 0.30 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
| ▸ | TGM1 | P22735 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18993786 | 0.76 | P2RX7 (0.34) | P2RX7MKNK1MKNK2TRIM24TRIM33 | |
| SCHEMBL22199160 | 0.72 | P2RX7 (0.41) | P2RX7MKNK1MKNK2CYP1A2CYP3A4 | |
| SCHEMBL18133177 | 0.71 | P2RX7 (0.38) | P2RX7MKNK1MKNK2MAPTTRIM24 | |
| SCHEMBL935465 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL4201170 | 0.69 | ALDH1A1 (0.37) | P2RX7MKNK1MKNK2MAPTTRIM24 | |
| SCHEMBL21094709 | 0.68 | P2RX7 (0.37) | P2RX7MKNK1MKNK2CYP1A2CYP3A4 | |
| SCHEMBL11173012 | 0.68 | TRIM24 (0.35) | P2RX7MKNK1MKNK2MAPTTRIM24 | |
| SCHEMBL312449 | 0.67 | — | — | |
| SCHEMBL14677805 | 0.67 | — | — | |
| SCHEMBL29948333 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246553-B2 | Organic fluorine compound and lubricant | SHOWA DENKO K.K. (JP) | 2019-04-02 | — | — | US | disclosed |
| US-20180127543-A1 | ORGANIC FLUORINE COMPOUND AND LUBRICANT | SHOWA DENKO K.K. (JP) | 2018-05-10 | — | — | US | disclosed |