SCHEMBL1899423

SCHEMBL1899423

[Zr]c1cccc2c1C1=Cc3ccccc3C1=N2

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.68
IDO1 P14902 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
APAF1 O14727 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30
MAPT P10636 1/20 0.30
TSHR P16473 1/20 0.30
HK1 P19367 1/20 0.30
GALK1 P51570 1/20 0.30
KMT2A Q03164 1/20 0.30
HKDC1 Q2TB90 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1820361 0.81 ABCG2 (0.68) ABCG2IDO1KDM4EMEN1APAF1
SCHEMBL4313626 0.81 ABCG2 (0.68) ABCG2IDO1KDM4EMEN1APAF1
SCHEMBL3507966 0.79 ABCG2 (0.66) ABCG2IDO1
Hydrochloric Acid SCHEMBL4458466 0.79 ABCG2 (0.66) ABCG2IDO1
SCHEMBL4448186 0.78 ABCG2 (0.64) ABCG2
SCHEMBL30019213 0.77 ABCG2 (0.62) ABCG2IDO1KDM4EMEN1APAF1
SCHEMBL261676 0.77 ABCG2 (0.62) ABCG2IDO1KDM4EMEN1APAF1
SCHEMBL9844742 0.75 ABCG2 (0.59) ABCG2
SCHEMBL2955387 0.74 ABCG2 (0.58) ABCG2
SCHEMBL6525398 0.72 ABCG2 (0.56) ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3040124-B1 METHOD FOR PRODUCING HYBRID-SUPPORTED METALLOCENE CATALYST LG CHEMICAL LTD (KR) 2018-08-01 EP disclosed
EP-2321369-A1 POLYETHYLENE THICK FILM AND PROCESS FOR PREPARING POLYETHYLENE Equistar Chemicals, LP (US) 2011-05-18 EP disclosed
US-7816478-B2 Polyethylene thick film and process for preparing polyethylene EQUISTAR CHEMICALS, LP (US) 2010-10-19 US disclosed
US-7781549-B2 Olefin polymerization process EQUISTAR CHEMICALS, LP (US) 2010-08-24 US disclosed
US-7781549-B2 Olefin polymerization process EQUISTAR CHEMICALS, LP (US) 2010-08-24 US disclosed
US-7776974-B2 Olefin polymerization process EQUISTAR CHEMICALS, LP (US) 2010-08-17 US disclosed
WO-2010027396-A1 POLYETHYLENE THICK FILM AND PROCESS FOR PREPARING POLYETHYLENE EQUISTAR CHEMICALS, LP (US) 2010-03-11 WO disclosed
US-20100055432-A1 thickness of 50 to 200 microns; Ethylene-Octene copolymer; bimodal molecular weight distribution; high impact strength; high modulus; two slurry zones with bridged and non-bridged zirconium complex catalysts; dialkylsilylene-bridged and unbridged cyclopentadienyl(indeno[2,1-b]indolyl)zirconium complex EQUISTAR CHEMICALS, LP 2010-03-04 US disclosed
US-7655740-B2 Olefin polymerization process EQUISTAR CHEMICALS, LP (US) 2010-02-02 US disclosed
US-7655740-B2 Olefin polymerization process EQUISTAR CHEMICALS, LP (US) 2010-02-02 US disclosed
US-20090062487-A1 Olefin polymerization process EQUISTAR CHEMICALS, LP 2009-03-05 US disclosed
US-20090062487-A1 Olefin polymerization process EQUISTAR CHEMICALS, LP 2009-03-05 US disclosed
US-20090062488-A1 Olefin polymerization process EQUISTAR CHEMICALS, LP 2009-03-05 US disclosed
EP-1525228-A2 CATALYSTS AND PROCESS FOR MAKING POLYOLEFINS Equistar Chemicals, LP (US) 2005-04-27 EP disclosed
US-6841500-B2 Bimetallic indenoindolyl catalysts EQUISTAR CHEMICALS, LP (US) 2005-01-11 US disclosed
US-6838410-B2 Catalysts for making polyolefins EQUISTAR CHEMICALS, LP (US) 2005-01-04 US disclosed
US-20040106514-A1 Bimetallic indenoindolyl catalysts EQUISTAR CHEMICALS, LP 2004-06-03 US disclosed
WO-2004013194-A2 CATALYSTS AND PROCESS FOR MAKING POLYOLEFINS EQUISTAR CHEMICALS, LP (US) 2004-02-12 WO disclosed
US-20040023791-A1 Catalysts for making polyolefins EQUISTAR CHEMICALS, LP 2004-02-05 US disclosed
US-6559251-B1 Ethylene copolymers is disclosed. Ethylene copolymerizes with an alpha -olefin in the presence of a catalyst system comprising an activator and a silica-supported, bridged indenoindolyl metal complex having \"open architecture.\ EQUISTAR CHEMICALS, LP 2003-05-06 US disclosed