SCHEMBL30019213

SCHEMBL30019213

C1=C2C(=Nc3ccccc32)c2ccccc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.62
IDO1 P14902 1/20 0.41
MAPT P10636 3/20 0.36
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 2/20 0.36
KDM4E B2RXH2 1/20 0.36
APAF1 O14727 1/20 0.36
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36
TSHR P16473 1/20 0.36
HK1 P19367 1/20 0.36
GALK1 P51570 1/20 0.36
HKDC1 Q2TB90 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SRC P12931 2/20 0.33
CTRB1 P17538 2/20 0.33
CCNE1 P24864 2/20 0.33
CDK2 P24941 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL261676 1.00 ABCG2 (0.62) ABCG2IDO1MAPTALDH1A1MEN1
SCHEMBL7464999 0.85 ABCG2 (0.55) ABCG2IDO1MAPTALDH1A1MEN1
SCHEMBL4499072 0.83 ABCG2 (0.46) ABCG2IDO1MAPTALDH1A1MEN1
SCHEMBL4510312 0.82 ABCG2 (0.45) ABCG2IDO1MAPTALDH1A1MEN1
SCHEMBL7733305 0.80 ABCG2 (0.50) ABCG2ALDH1A1TSHRHSD17B10MAPK1
SCHEMBL1820361 0.77 ABCG2 (0.68) ABCG2IDO1MAPTALDH1A1MEN1
SCHEMBL4313626 0.77 ABCG2 (0.68) ABCG2IDO1MAPTALDH1A1MEN1
SCHEMBL725971 0.77 ABCG2 (0.51) ABCG2IDO1
SCHEMBL1899423 0.77 ABCG2 (0.68) ABCG2IDO1MAPTALDH1A1MEN1
SCHEMBL527160 0.76 ABCG2 (0.46) ABCG2IDO1MAPTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117164506-B Preparation method of indeno [1,2-b ] indol-10 (5H) -one compound 浙江理工大学 2025-10-24 CN disclosed
CN-117843550-B 10-Perfluoroalkyl-5, 10-indano [1,2-b ] indole compound and synthesis method thereof 南京林业大学 2025-02-25 CN disclosed
US-12053465-B2 KCC2 expression enhancing compounds and uses thereof WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2024-08-06 US disclosed
CN-117980314-A Olefin polymerization catalyst system and polymerization process 诺瓦化学品(国际)股份有限公司 2024-05-03 CN disclosed
CN-117843550-A 10-perfluoroalkyl-5, 10-indano [1,2-b ] indole compound and synthesis method thereof 南京林业大学 2024-04-09 CN disclosed
CN-117164506-A Preparation method of indeno [1,2-b ] indol-10 (5H) -one compound 浙江理工大学 2023-12-05 CN disclosed
CN-117164506-A Preparation method of indeno [1,2-b ] indol-10 (5H) -one compound 浙江理工大学 2023-12-05 CN disclosed
CN-116768785-A Synthesis method of spirofluorene-containing indole derivative structure 西安欧得光电材料有限公司 2023-09-19 CN disclosed
CN-116410368-A Olefin polymerization catalyst composition, and preparation method and application thereof 中国石油天然气股份有限公司 2023-07-11 CN disclosed
CN-116410353-A Olefin polymerization catalyst composition and preparation method and application thereof 中国石油天然气股份有限公司 2023-07-11 CN disclosed
CN-116063223-A 10-perfluoroalkyl-5, 10-indano [1,2-b ] indole compound and synthesis method thereof 南京林业大学 2023-05-05 CN disclosed
US-20220378782-A1 KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2022-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220378782-A1 KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF MECP2, SLC1A2, GRIN2C ABCG2 1451/4885IDO1 4516/4885MAPT 1725/4885
US-12053465-B2 KCC2 expression enhancing compounds and uses thereof MECP2, SLC1A2, GRIN2C ABCG2 1451/4885IDO1 4516/4885MAPT 1725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.