SCHEMBL4448186

SCHEMBL4448186

C[Si](C)(c1cccc2c1C1=Cc3ccccc3C1=N2)c1cccc2c1C1=Cc3ccccc3C1=N2

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1820361 0.78 ABCG2 (0.68) ABCG2
SCHEMBL4313626 0.78 ABCG2 (0.68) ABCG2
SCHEMBL1899423 0.78 ABCG2 (0.68) ABCG2
SCHEMBL3507966 0.77 ABCG2 (0.66) ABCG2
Hydrochloric Acid SCHEMBL4458466 0.77 ABCG2 (0.66) ABCG2
SCHEMBL9844742 0.75 ABCG2 (0.59) ABCG2
SCHEMBL261676 0.75 ABCG2 (0.62) ABCG2
SCHEMBL30019213 0.75 ABCG2 (0.62) ABCG2
SCHEMBL2955387 0.74 ABCG2 (0.58) ABCG2
SCHEMBL4448185 0.72 ABCG2 (0.38) ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1567561-B1 BIMETALLIC INDENOINDOLYL CATALYSTS EQUISTAR CHEM LP (US) 2009-05-27 EP disclosed
EP-1567561-A1 BIMETALLIC INDENOINDOLYL CATALYSTS Equistar Chemicals, LP (US) 2005-08-31 EP disclosed
US-6841500-B2 Bimetallic indenoindolyl catalysts EQUISTAR CHEMICALS, LP (US) 2005-01-11 US disclosed
WO-2004050718-A1 BIMETALLIC INDENOINDOLYL CATALYSTS EQUISTAR CHEMICALS, LP (US) 2004-06-17 WO disclosed
US-20040106514-A1 Bimetallic indenoindolyl catalysts EQUISTAR CHEMICALS, LP 2004-06-03 US disclosed