Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967167 | 0.80 | DRD2 (0.37) | HTR2ASLC6A4DRD2HRH1LMNA | |
| SCHEMBL18994464 | 0.79 | GLS (0.43) | GLSLMNA | |
| SCHEMBL12788682 | 0.70 | GLS (0.60) | GLSLMNA | |
| SCHEMBL23080253 | 0.69 | GLS (0.32) | GLS | |
| SCHEMBL24967869 | 0.68 | EPHX2 (0.34) | — | |
| SCHEMBL21025402 | 0.68 | EPHX2 (0.34) | — | |
| SCHEMBL23985340 | 0.66 | DRD2 (0.39) | HTR2ASLC6A4DRD2HRH1 | |
| SCHEMBL12165181 | 0.63 | GAA (0.38) | HTR2ASLC6A4DRD2HRH1 | |
| SCHEMBL1764531 | 0.63 | — | — | |
| SCHEMBL21325428 | 0.63 | SLC6A2 (0.36) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682998-B2 | Fused heterocyclic compounds as ion channel modulators | GILEAD SCIENCES, INC. (US) | 2017-06-20 | — | — | US | disclosed |