SCHEMBL1899460

SCHEMBL1899460

C=CC(=O)O[SiH2]C(C)(C)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.39
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28616966 0.79 TSHR (0.35) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL10400394 0.77
SCHEMBL947096 0.73 TSHR (0.32) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL21811168 0.73 TSHR (0.37) TSHR
SCHEMBL5142180 0.73 CYP2C19 (0.37) ALDH1A1CYP3A4HPGD
SCHEMBL1898445 0.72 TSHR (0.39) TSHRALDH1A1
SCHEMBL7712185 0.70 TSHR (0.45) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL2740738 0.70 TSHR (0.45) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL20626572 0.70 TSHR (0.45) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL3139306 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1724310-B1 Antifouling coating composition, coating film therefrom, underwater material covered with the coating film and antifouling method CHUGOKU MARINE PAINTS (JP) 2018-10-31 EP disclosed
EP-1342756-B2 Antifouling coating composition, coating film therefrom, underwater material covered with the coating film and antifouling method CHUGOKU MARINE PAINTS (JP) 2015-06-24 EP disclosed
US-20110198730-A1 HYPERBRANCHED POLYMER SYNTHESIZING METHOD, HYPERBRANCHED POLYMER, RESIST COMPOSITION, SEMICONDUCTOR INTEGRATED CIRCUIT, AND SEMICONDUCTOR INTEGRATED CIRCUIT FABRICATION METHOD LION CORPORATION 2011-08-18 US disclosed
US-20110101503-A1 HYPERBRANCHED POLYMER SYNTHESIZING METHOD, HYPERBRANCHED POLYMER, RESIST COMPOSITION, SEMICONDUCTOR INTEGRATED CIRCUIT, AND SEMICONDUCTOR INTEGRATED CIRCUIT FABRICATION METHOD LION CORPORATION (JP) 2011-05-05 US disclosed
US-20080160449-A1 Photoresist polymer having nano-smoothness and etching resistance, and resist composition LION CORPORATION (JP) 2008-07-03 US disclosed
US-20070148585-A1 Hyperbranched polymer, production method therefor and resist composition containing hyperbranched polymer LION CORPORATION. 2007-06-28 US disclosed
EP-1724310-A1 Antifouling coating composition, coating film therefrom, underwater material covered with the coating film and antifouling method CHUGOKU MARINE PAINTS, LTD. (JP) 2006-11-22 EP disclosed
EP-1342756-B1 Antifouling coating composition, coating film therefrom, underwater material covered with the coating film and antifouling method CHUGOKU MARINE PAINTS (JP) 2006-11-15 EP disclosed
EP-1698645-A1 HYPERBRANCHED POLYMER, PROCESS FOR PRODUCING THE SAME AND RESIST COMPOSITION CONTAINING THE HYPERBRANCHED POLYMER Lion Corporation (JP) 2006-09-06 EP disclosed
EP-1016681-B1 Silyl (meth)acrylate copolymers, processes for preparing the same, antifouling paint compositions containing the silyl (meth)acrylate copolymers, antifouling coating films formed from the antifouling paint compositions, antifouling methods using the antifouling paint compositions, and hulls or underwater structures coated with the antifouling coating films CHUGOKU MARINE PAINTS (JP) 2005-08-17 EP disclosed
US-6916860-B2 Antifouling coating composition, coating film therefrom, base material covered with the coating film and antifouling method CHUGOKU MARINE PAINTS, LTD. (JP) 2005-07-12 US disclosed
US-6828030-B2 Nonstannic paint of blocks of unsaturated carboxylic acid silyl ester and unsaturated monomer units and an ether containing mercapto CHUGOKU MARINE PAINTS, LTD. (JP) 2004-12-07 US disclosed
US-20030207962-A1 Antifouling coating composition, coating film therefrom, base material covered with the coating film and antifouling method CHUGOKU MARINE PAINTS, LTD. (JP) 2003-11-06 US disclosed
EP-1342756-A1 Antifouling coating composition, coating film therefrom, underwater material covered with the coating film and antifouling method CHUGOKU MARINE PAINTS, LTD. (JP) 2003-09-10 EP disclosed
EP-1201700-B1 (Poly)oxyalkylene block silyl ester copolymer, antifouling coating composition, antifouling coating formed from antifouling coating composition, antifouling method using antifouling coating composition and hull or underwater structure covered with antifouling coating CHUGOKU MARINE PAINTS (JP) 2003-05-14 EP disclosed
US-20020156224-A1 Novel (poly)oxyalkylene block silyl ester copolymer, antifouling coating composition, antifouling coating formed from antifouling coating composition, antifouling method using antifouling coating composition and hull or underwater structure covered with antifouling coating CHUGOKU MARINE PAINTS, LTD. 2002-10-24 US disclosed
US-6458878-B1 THE METHOD OF ANTIFOULING A HULL OR AN UNDERWATER STRUCTURE ACCORDING TO THE INVENTION EMPLOYS THE ANTIFOULING PAINT COMPOSITION DESCRIBED ABOVE. CHUOGOKU MARINE PAINTS, LTD. (JP) 2002-10-01 US disclosed
EP-1201700-A1 (Poly)oxyalkylene block silyl ester copolymer, antifouling coating composition, antifouling coating formed from antifouling coating composition, antifouling method using antifouling coating composition and hull or underwater structure covered with antifouling coating CHUGOKU MARINE PAINTS, LTD. (JP) 2002-05-02 EP disclosed
EP-1016681-A2 Silyl (meth)acrylate copolymers, processes for preparing the same, antifouling paint compositions containing the silyl (meth)acrylate copolymers, antifouling coating films formed from the antifouling paint compositions, antifouling methods using the antifouling paint compositions, and hulls or underwater structures coated with the antifouling coating films CHUGOKU MARINE PAINTS, LTD. (JP) 2000-07-05 EP disclosed