SCHEMBL5142180

SCHEMBL5142180

C=CC(=O)O[SiH2]C(C)(C)C(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.37
RIPK1 Q13546 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
THRB P10828 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
AKT1 P31749 1/20 0.33
MAPT P10636 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
NR3C1 P04150 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1899460 0.73 TSHR (0.39) ALDH1A1CYP3A4HPGD
SCHEMBL10890693 0.72 THRB (0.40) CYP2C19L3MBTL1THRBHCAR2KMT2A
SCHEMBL20561321 0.72 KMT2A (0.42) CYP2C19ATML3MBTL1CNR1CNR2
SCHEMBL5313288 0.71 KMT2A (0.35) RIPK1ATML3MBTL1CNR1CNR2
SCHEMBL1493626 0.70 ATM (0.41) CYP2C19RIPK1ATML3MBTL1THRB
SCHEMBL14845446 0.69 RIPK1 (0.41) CYP2C19RIPK1ATML3MBTL1THRB
SCHEMBL28616966 0.68 TSHR (0.35) THRBALDH1A1CYP3A4HPGD
SCHEMBL704144 0.68 ATM (0.39) RIPK1ATML3MBTL1CNR1CNR2
SCHEMBL705924 0.68 RIPK1 (0.40) RIPK1ATML3MBTL1CNR1CNR2
SCHEMBL5837886 0.68 TDP1 (0.37) CYP2C19ATMTHRBALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7297727-B2 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. (US) 2007-11-20 US disclosed
EP-1479737-B1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC (US) 2006-08-16 EP disclosed
EP-1479737-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions Atofina Chemicals, Inc. (US) 2004-11-24 EP disclosed
US-20040138332-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. 2004-07-15 US disclosed
US-20030225184-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. 2003-12-04 US disclosed
EP-1367100-A1 Triarylsilyl (meth) acryloyl-containing polymers for marine coating compositions ATOFINA CHEMICALS, INC. (US) 2003-12-03 EP disclosed