Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26011755 | 0.93 | NPC1 (0.38) | NPC1RAB9ACASP3SMN1; SMN2SENP8 | |
| SCHEMBL25559299 | 0.91 | SMN1; SMN2 (0.39) | NPC1RAB9ACASP3SMN1; SMN2SENP8 | |
| SCHEMBL15702903 | 0.90 | FFAR1 (0.41) | NPC1RAB9ACASP3SMN1; SMN2SENP8 | |
| SCHEMBL14749885 | 0.88 | MAPT (0.33) | NPC1RAB9ACASP3SMN1; SMN2SENP8 | |
| SCHEMBL14749976 | 0.84 | MAOB (0.42) | NPC1RAB9ACASP3SMN1; SMN2SENP8 | |
| SCHEMBL19077749 | 0.84 | MAPT (0.35) | SMN1; SMN2MAPTHIF1ACHRNB2CHRNB4 | |
| SCHEMBL19860053 | 0.82 | MAPT (0.34) | NPC1RAB9ACASP3SMN1; SMN2SENP8 | |
| SCHEMBL19077748 | 0.81 | MAPT (0.35) | SMN1; SMN2PTPN1MAPTHIF1ACHRNB2 | |
| SCHEMBL12299710 | 0.80 | ALDH1A1 (0.34) | NPC1RAB9ACASP3SMN1; SMN2SENP8 | |
| SCHEMBL22858574 | 0.77 | GCGR (0.42) | NPC1RAB9ACASP3SMN1; SMN2SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174957-A1 | POLYPHENYLENE ETHER OLIGOMER AND HIGH-FREQUENCY COPPER CLAD LAMINATE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174957-A1 | POLYPHENYLENE ETHER OLIGOMER AND HIGH-FREQUENCY COPPER CLAD LAMINATE | CPNE4, COPE, HLA-DRB1 | NPC1 2245/4885RAB9A 2060/4885CASP3 3251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.