SCHEMBL1899771

SCHEMBL1899771

Oc1[nH]nnc1Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 4/20 0.43
AR P10275 1/20 0.42
ALDH1A1 P00352 2/20 0.41
CYP2C9 P11712 2/20 0.41
HPGD P15428 2/20 0.41
HCAR2 Q8TDS4 1/20 0.41
CALM1 P0DP23 1/20 0.41
LTB4R Q15722 1/20 0.41
BCL2 P10415 1/20 0.39
BCL2L1 Q07817 1/20 0.39
HTR2C P28335 1/20 0.39
IDH1 O75874 1/20 0.37
HTT P42858 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
HSD17B10 Q99714 1/20 0.37
LMNA P02545 1/20 0.37
PRNP P04156 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL8182334 0.98 PARP1 (0.42) PARP1ARALDH1A1CYP2C9HPGD
Resorcinol SCHEMBL10620240 0.85 PARP1 (0.43) PARP1ALDH1A1HPGDHCAR2BCL2L1
SCHEMBL28223167 0.80 DAO (0.41) RXFP1DAO
SCHEMBL1203617 0.78 LTB4R (0.50) PARP1ARALDH1A1CYP2C9HPGD
SCHEMBL6713000 0.77 PARP1 (0.42) PARP1ARALDH1A1CYP2C9HPGD
SCHEMBL9525223 0.77 LTB4R (0.49) PARP1ARALDH1A1CYP2C9HPGD
SCHEMBL21531465 0.77 CALM1 (0.46) PARP1ARALDH1A1CYP2C9HPGD
SCHEMBL5600491 0.77 HTR2C (0.45) PARP1ARALDH1A1CYP2C9HPGD
SCHEMBL305311 0.77 PARP1 (0.42) PARP1ARALDH1A1CYP2C9HPGD
SCHEMBL17296040 0.76 PARP1 (0.43) PARP1ALDH1A1HPGDBCL2L1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119101410-A Plasma cutting protection liquid and application thereof 浙江奥首材料科技有限公司 2024-12-10 CN claimed
CN-112021051-A Kiwi root rot control method 台州市农业科学研究院 2020-12-04 CN claimed
CN-119101410-A Plasma cutting protection liquid and application thereof 浙江奥首材料科技有限公司 2024-12-10 CN disclosed
US-11834553-B2 Alkoxylation methods NEKTAR THERAPEUTICS (US) 2023-12-05 US disclosed
US-11672776-B2 Multi-arm polymeric alkanoate conjugates NEKTAR THERAPEUTICS (US) 2023-06-13 US disclosed
US-20220079936-A1 MULTI-ARM POLYMER PRODRUGS NEKTAR THERAPEUTICS (US) 2022-03-17 US disclosed
US-20210024693-A1 ALKOXYLATION METHODS NEKTAR THERAPEUTICS 2021-01-28 US disclosed
CN-112021051-A Kiwi root rot control method 台州市农业科学研究院 2020-12-04 CN disclosed
US-10463659-B2 Multi-arm polymer prodrugs NEKTAR THERAPEUTICS (US) 2019-11-05 US disclosed
EP-3498754-A1 ALKOXYLATION METHODS Nektar Therapeutics (US) 2019-06-19 EP disclosed
EP-2501413-B1 ACID SALT FORMS OF POLYMER-DRUG CONJUGATES NEKTAR THERAPEUTICS (US) 2019-03-27 EP disclosed
WO-1994027627-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1994-12-08 WO disclosed
WO-1994007511-A1 ANTIBODIES DETECTING STROMELYSIN CLEAVAGE PRODUCTS MERCK & CO., INC. (US) 1994-04-14 WO disclosed
EP-0486478-A2 Renin-inhibiting peptides THE UPJOHN COMPANY (US) 1992-05-20 EP disclosed
US-4880781-A HYPOTENSIVE AGENTS THE UPJOHN COMPANY (US) 1989-11-14 US disclosed
WO-1988004665-A1 A NEW PERTUSSIS TOXIN DERIVED POLYPEPTIDE AND APPLICATIONS THEREOF TRION FORSKNING- OCH UTVECKLINGS AKTIEBOLAG (SE) 1988-06-30 WO disclosed
WO-1988002754-A1 NEW PEPTIDES AND APPLICATIONS THEREOF TRION FORSKNING- OCH UTVECKLINGS AKTIEBOLAG (SE) 1988-04-21 WO disclosed
WO-1987007150-A1 RECEPTOR-TARGETED DRUG DELIVERY SYSTEMS THE JOHNS HOPKINS UNIVERSITY (US) 1987-12-03 WO disclosed
EP-0054862-B1 SUBSTITUTED DIPEPTIDES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THE INHIBITION OF ENKEPHALINASE SCHERING CORPORATION (US) 1985-11-27 EP disclosed
EP-0054862-A1 Substituted dipeptides, processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase SCHERING CORPORATION (US) 1982-06-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11672776-B2 Multi-arm polymeric alkanoate conjugates ALK, ALKBH3, PAICS PARP1 55/4885AR 648/4885ALDH1A1 74/4885
US-10463659-B2 Multi-arm polymer prodrugs PAICS, CD38, ENTPD1 PARP1 21/4885AR 2328/4885ALDH1A1 250/4885
US-20210024693-A1 ALKOXYLATION METHODS ALK, ALKBH3, SLC10A1 PARP1 1347/4885AR 483/4885ALDH1A1 282/4885
US-11834553-B2 Alkoxylation methods ALK, ALKBH3, SLC10A1 PARP1 1347/4885AR 483/4885ALDH1A1 282/4885
US-20220079936-A1 MULTI-ARM POLYMER PRODRUGS PAICS, CD38, ENTPD1 PARP1 21/4885AR 2328/4885ALDH1A1 250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.