Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1203617 | 0.78 | LTB4R (0.50) | PARP1ARCYP2C9HPGDALDH1A1 | |
| SCHEMBL5600491 | 0.77 | HTR2C (0.45) | PARP1ARCYP2C9HPGDALDH1A1 | |
| SCHEMBL21531465 | 0.77 | CALM1 (0.46) | PARP1ARCYP2C9HPGDALDH1A1 | |
| SCHEMBL1899771 | 0.77 | PARP1 (0.43) | PARP1ARCYP2C9HPGDALDH1A1 | |
| SCHEMBL6713000 | 0.77 | PARP1 (0.42) | PARP1ARCYP2C9HPGDALDH1A1 | |
| SCHEMBL9525223 | 0.77 | LTB4R (0.49) | PARP1ARCYP2C9HPGDALDH1A1 | |
| Water SCHEMBL8182334 | 0.76 | PARP1 (0.42) | PARP1ARCYP2C9HPGDALDH1A1 | |
| SCHEMBL16050773 | 0.76 | NR1H2 (0.42) | PARP1ARCYP2C9HPGDALDH1A1 | |
| SCHEMBL18005802 | 0.74 | PARP1 (0.40) | PARP1ARCYP2C9HPGDALDH1A1 | |
| SCHEMBL28146928 | 0.73 | PARP1 (0.39) | PARP1ARCYP2C9HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093279-B2 | Compound | STERIX LIMITED (GB) | 2012-01-10 | — | — | US | disclosed |
| US-20100173963-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-07-08 | — | — | US | disclosed |
| EP-1641788-A1 | PREPARATION OF N2-ALKYLATED 1,2,3-TRIAZOLES | Warner-Lambert Company LLC (US) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005000841-A1 | PREPARATION OF N2-ALKYLATED 1,2,3-TRIAZOLES | WARNER-LAMBERT COMPANY LLC (US) | 2005-01-06 | — | — | WO | disclosed |
| US-20040266848-A1 | Preparation of N2-alkylated 1,2,3-triazoles | HADD MARK ALLEN (US) | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266848-A1 | Preparation of N2-alkylated 1,2,3-triazoles | PPARA, PPARG, PPARD | PARP1 1245/4885AR 593/4885CYP2C9 1301/4885 |
| US-20100173963-A1 | COMPOUND | CBR3, CBR1, OXSR1 | PARP1 2755/4885AR 488/4885CYP2C9 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.