SCHEMBL1899787

SCHEMBL1899787

O=C=Nc1ccc(SP(=O)(O)O)cc1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
TRPA1 O75762 1/20 0.35
HSD17B10 Q99714 1/20 0.34
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9575174 0.77 CYP3A4 (0.40) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL739866 0.74 CYP3A4 (0.54) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL484003 0.74 CYP3A4 (0.54) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL15430 0.73 CYP3A4 (0.70) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL4389691 0.72 CYP3A4 (0.42) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL11856992 0.71 CYP3A4 (0.50) CYP3A4TSHRMAPK1TDP1TRPA1
Phosphoric Acid SCHEMBL55726 0.71 CA2 (0.46) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL27702459 0.71 CYP3A4 (0.50) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL546217 0.71 CYP3A4 (0.50) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL27741428 0.71 CYP3A4 (0.67) CYP3A4TSHRMAPK1TDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2496549-B1 NEW, NON-CRYSTALLISING METHACRYLATE, ITS MANUFACTURE AND APPLICATION BAYER IP GMBH (DE) 2014-10-08 EP disclosed
EP-2496549-A2 NOVEL NON-CRYSTALLIZING METHACRYLATES, PRODUCTION AND USE THEREOF Bayer MaterialScience AG (DE) 2012-09-12 EP disclosed
WO-2011054818-A2 NOVEL NON-CRYSTALLIZING METHACRYLATES, PRODUCTION AND USE THEREOF BAYER MATERIALSCIENCE AG (DE) 2011-05-12 WO disclosed
EP-0524518-A2 Urea extended polyisocyanates MILES INC. (US) 1993-01-27 EP disclosed
US-5128407-A Polybiuret MILES INC. (US) 1992-07-07 US disclosed
US-RE30676-E POLYETHERPOLYOL OR POLYESTERPOLYOL, AMINE DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1981-07-14 US disclosed
US-4113667-A SPECIFIC AMINES DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1978-09-12 US disclosed
US-4088614-A POLYETHERPOLYOL, POLYESTERPOLYOL, POLYISOCYANATE, WATER, FOAMING AGENT, EMULSIFYING AGENT DAI-ICHI KOGYO SEIYAKU CO., LTD. (JA) 1978-05-09 US disclosed