SCHEMBL739866

SCHEMBL739866

O=C=Nc1ccc(SSc2ccc(N=C=O)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.54
TSHR P16473 1/20 0.54
MAPK1 P28482 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
TRPA1 O75762 1/20 0.42
CYP1A2 P05177 1/20 0.39
HSD17B10 Q99714 2/20 0.36
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MGLL Q99685 1/20 0.33
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL484003 0.85 CYP3A4 (0.54) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL2888228 0.85 CYP3A4 (0.45) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL15430 0.84 CYP3A4 (0.70) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL28944560 0.82 MIF (0.42) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL29218994 0.81 CYP3A4 (0.50) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL27702459 0.81 CYP3A4 (0.50) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL546217 0.81 CYP3A4 (0.50) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL11856992 0.81 CYP3A4 (0.50) CYP3A4TSHRMAPK1TDP1TRPA1
Water SCHEMBL28889229 0.81 CYP3A4 (0.67) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL27741428 0.81 CYP3A4 (0.67) CYP3A4TSHRMAPK1TDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 571 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4849262-A Pigment printing pastes and dyeing liquors containing stable dispersions of finely divided solid polyisocyanates BASF AKTIENGESELLSCHAFT (DE) 1989-07-18 US claimed
US-12606692-B2 Spectacle lens HOYA LENS THAILAND LTD. (TH) 2026-04-21 US disclosed
EP-3983466-B1 AQUEOUS POLYURETHANE DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2026-02-18 EP disclosed
EP-3778170-B1 METHOD FOR MANUFACTURING OPTICAL MEMBER HOYA LENS THAILAND LTD (TH) 2026-01-28 EP disclosed
US-12384124-B2 Method for producing polarizing lens, polarizing film and polarizing lens HOYA LENS THAILAND LTD. (TH) 2025-08-12 US disclosed
EP-4396248-B1 AQUEOUS POLYURETHANE-UREA DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2025-08-06 EP disclosed
EP-3689932-B1 METHOD FOR MANUFACTURING OPTICAL MEMBER RESIN, OPTICAL MEMBER RESIN, SPECTACLE LENS, AND SPECTACLES HOYA LENS THAILAND LTD (TH) 2025-07-30 EP disclosed
US-12359016-B2 Method of preparing low haze polymer compositions for use in high refractive index optical materials PPG INDUSTRIES OHIO, INC. (US) 2025-07-15 US disclosed
US-20250188215-A1 AQUEOUS POLYURETHANE DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2025-06-12 US disclosed
US-20250188024-A1 METHOD OF PRODUCING PENTAERYTHRITOL MERCAPTOCARBOXYLATE, POLYMERIZABLE COMPOSITION, RESIN, OPTICAL MATERIAL, AND SPECTACLE LENS HOYA LENS THAILAND LTD. (TH) 2025-06-12 US disclosed
US-4946923-A S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-08-07 US disclosed
US-4929707-A Polyurethane base lens resin, plastic lens comprising the resin and preparation method of the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-05-29 US disclosed
EP-0330363-A2 Highly-refractive plastic lens and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
EP-0329386-A2 S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
EP-0130462-A2 Printed circuits AMOCO CORPORATION (US) 1985-01-09 EP disclosed
EP-0070324-A1 Apparatus for producing a curable polyurethane froth UNION CARBIDE CORPORATION (US) 1983-01-26 EP disclosed
EP-0069163-A1 A frothable polyurethane composition and a cellular foam produced therefrom UNION CARBIDE CORPORATION (US) 1983-01-12 EP disclosed
US-4316875-A Apparatus for producing a curable polyurethane froth UNION CARBIDE CORPORATION (US) 1982-02-23 US disclosed
US-4275172-A Frothable polyurethane composition and a cellular foam produced therefrom suitable for use in joints between wallboards UNION CARBIDE CORPORATION (US) 1981-06-23 US disclosed
US-3994742-A SULFUR COMPOUNDS CONTAINING AT LEAST TWO AMINO OR IMINO GROUPS PPG INDUSTRIES, INC. (US) 1976-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606692-B2 Spectacle lens POT1, TCOF1, CRY1 CYP3A4 4631/4885TSHR 329/4885MAPK1 1827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.