Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 8/20 | 0.64 |
| ▸ | CKS1B | P61024 | 1/20 | 0.56 |
| ▸ | SKP1 | P63208 | 1/20 | 0.56 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NAMPT | P43490 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18995987 | 0.93 | SLC6A7 (0.64) | SLC6A7ALDH1A1MAPTHPGDCKS1B | |
| SCHEMBL19001282 | 0.88 | ALDH1A1 (0.69) | SLC6A7ALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL19001286 | 0.84 | SLC6A7 (0.51) | SLC6A7ALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL3575539 | 0.83 | SLC6A7 (1.00) | SLC6A7ALDH1A1HPGDCKS1BSKP1 | |
| SCHEMBL25010218 | 0.82 | ALDH1A1 (0.76) | SLC6A7ALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL18995928 | 0.82 | ALDH1A1 (0.62) | SLC6A7ALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL11080932 | 0.81 | SLC6A7 (0.85) | SLC6A7ALDH1A1CKS1BSKP1SKP2 | |
| SCHEMBL10211687 | 0.80 | NAMPT (0.54) | SLC6A7NAMPT | |
| SCHEMBL15378727 | 0.80 | SLC6A7 (0.50) | SLC6A7ALDH1A1MAPTHPGDNAMPT | |
| SCHEMBL20467488 | 0.80 | HPGD (0.82) | ALDH1A1MAPTHPGDNAMPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174704-A1 | QUINOXALINE COMPOUNDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174704-A1 | QUINOXALINE COMPOUNDS AND USES THEREOF | NAMPT, NQO2, NNMT | SLC6A7 1939/4885ALDH1A1 1374/4885MAPT 2452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.