Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 7/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17448273 | 0.87 | CTSK (0.49) | CTSKL3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL23901065 | 0.86 | SMN1; SMN2 (0.44) | CTSKL3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18885737 | 0.86 | LMNA (0.44) | CTSKL3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL24760365 | 0.85 | KCNA5 (0.47) | CTSKL3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL24760208 | 0.85 | L3MBTL1 (0.48) | L3MBTL1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL24270673 | 0.83 | L3MBTL1 (0.48) | CTSKL3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL22388985 | 0.83 | L3MBTL1 (0.45) | CTSKL3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL24760348 | 0.82 | CTSK (0.46) | CTSKLMNACTSSCTSLMEN1 | |
| SCHEMBL25062103 | 0.82 | TOP2A (0.49) | CTSKLMNACTSSCTSLMEN1 | |
| SCHEMBL19750475 | 0.82 | LMNA (0.63) | CTSKL3MBTL1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10293055-B2 | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-05-21 | — | — | US | disclosed |
| US-10232051-B2 | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-03-19 | — | — | US | disclosed |
| US-20170173176-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | SUZHOU M-CONJ BIOTECH CO., LTD. (CN) | 2017-06-22 | — | — | US | disclosed |
| US-20170173168-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | SUZHOU M-CONJ BIOTECH CO., LTD. (CN) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170173176-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | AADAC, EPCAM, DCLRE1A | CTSK 1439/4885L3MBTL1 1920/4885MAPT 4288/4885 |
| US-10293055-B2 | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule | AADAC, EPCAM, DCLRE1A | CTSK 1439/4885L3MBTL1 1920/4885MAPT 4288/4885 |
| US-20170173168-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | AADAC, EPCAM, DCLRE1A | CTSK 1439/4885L3MBTL1 1920/4885MAPT 4288/4885 |
| US-10232051-B2 | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule | AADAC, EPCAM, DCLRE1A | CTSK 1439/4885L3MBTL1 1920/4885MAPT 4288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.