Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 2/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL985791 | 0.88 | THRA (0.48) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL1899456 | 0.85 | HPGD (0.41) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL17530462 | 0.80 | FOLH1 (0.51) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL9251505 | 0.80 | CYP3A4 (0.44) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL1898068 | 0.80 | TSHR (0.47) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL8954925 | 0.79 | TSHR (0.76) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL1896570 | 0.77 | ALDH1A1 (0.44) | TSHRCYP3A4ALDH1A1HSD17B10LMNA | |
| SCHEMBL1901143 | 0.76 | KMT2A (0.42) | TSHRTDP1L3MBTL1CYP3A4ALDH1A1 | |
| SCHEMBL7576211 | 0.76 | ALDH1A1 (0.68) | TSHRCYP3A4ALDH1A1HSD17B10LMNA | |
| SCHEMBL1896070 | 0.76 | ALDH1A1 (0.43) | TSHRL3MBTL1CYP3A4ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110101503-A1 | HYPERBRANCHED POLYMER SYNTHESIZING METHOD, HYPERBRANCHED POLYMER, RESIST COMPOSITION, SEMICONDUCTOR INTEGRATED CIRCUIT, AND SEMICONDUCTOR INTEGRATED CIRCUIT FABRICATION METHOD | LION CORPORATION (JP) | 2011-05-05 | — | — | US | disclosed |