Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL827154 | 0.92 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL12370722 | 0.86 | ALDH1A1 (0.48) | ALDH1A1LMNASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL10338842 | 0.82 | LMNA (0.43) | ALDH1A1LMNASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL28132523 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2HSD17B10ALOX15 | |
| SCHEMBL17011655 | 0.80 | ALDH1A1 (0.43) | ALDH1A1HPGDHSD17B10ALOX15ALOX12 | |
| SCHEMBL17011647 | 0.80 | ALDH1A1 (0.43) | ALDH1A1HPGDHSD17B10ALOX15ALOX12 | |
| SCHEMBL11173586 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL11174842 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL12370703 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL12370698 | 0.76 | HSD17B10 (0.44) | ALDH1A1LMNASMN1; SMN2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307342-B1 | DIGLYCIDIC ETHER DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2017-06-21 | — | — | EP | disclosed |