SCHEMBL827154

SCHEMBL827154

C=CCOc1c(Br)cc(C(C)(C)c2cc(Br)c(OCC=C)c(Br)c2)cc1Br

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
LMNA P02545 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
HPGD P15428 2/20 0.42
HSD17B10 Q99714 2/20 0.42
ALOX15 P16050 2/20 0.42
ALOX12 P18054 2/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
CASP1 P29466 1/20 0.42
RECQL P46063 1/20 0.42
HIF1A Q16665 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MEN1 O00255 6/20 0.39
KMT2A Q03164 6/20 0.39
HTT P42858 3/20 0.39
KDM4E B2RXH2 2/20 0.37
PKM P14618 1/20 0.37
CHEK1 O14757 1/20 0.37
DAPK3 O43293 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12370722 0.94 ALDH1A1 (0.48) ALDH1A1LMNASMN1; SMN2HPGDHSD17B10
SCHEMBL19001641 0.92 ALDH1A1 (0.47) ALDH1A1LMNASMN1; SMN2HPGDHSD17B10
SCHEMBL10338842 0.89 LMNA (0.43) ALDH1A1LMNASMN1; SMN2HPGDHSD17B10
SCHEMBL28132523 0.87 ALDH1A1 (0.43) ALDH1A1LMNASMN1; SMN2HSD17B10ALOX15
SCHEMBL11173586 0.85 ALDH1A1 (0.47) ALDH1A1LMNASMN1; SMN2HPGDHSD17B10
SCHEMBL11174842 0.84 ALDH1A1 (0.46) ALDH1A1LMNASMN1; SMN2HPGDHSD17B10
SCHEMBL12370703 0.83 ALDH1A1 (0.50) ALDH1A1LMNASMN1; SMN2HPGDHSD17B10
SCHEMBL12370698 0.82 HSD17B10 (0.44) ALDH1A1LMNASMN1; SMN2HPGDHSD17B10
SCHEMBL13483224 0.81 PTGS1 (0.35) ALDH1A1LMNASMN1; SMN2HPGDHSD17B10
SCHEMBL2270833 0.81 ALDH1A1 (0.49) ALDH1A1LMNASMN1; SMN2HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4049841-B1 HYBRID RESIN COMPOSITION CUBICURE GMBH (AT) 2026-03-18 EP claimed
US-12479969-B2 Method for preparing flame retardant aid and flame retardant resin composition comprising flame retardant aid prepared by same LG CHEM, LTD. (KR) 2025-11-25 US claimed
US-12390987-B2 Hybrid resin composition for the 3D-printing of objects CUBICURE GMBH (AT) 2025-08-19 US claimed
US-12202780-B1 Process for debromination of novel brominated flame retardants using Zn-based additives UNITED ARAB EMIRATES UNIVERSITY (AE) 2025-01-21 US claimed
CN-116425436-B Method for cooperatively disposing waste small packaging barrel by cement kiln 浙江红狮环保股份有限公司 2024-12-17 CN claimed
EP-3907266-B1 FLAME RETARDANT RESIN COMPOSITION AND METHOD FOR PRODUCING THE SAME LG CHEMICAL LTD (KR) 2024-11-27 EP claimed
CN-116178855-B High-flame-retardance high-oil-resistance plastic and preparation method thereof 江苏华亚电缆有限公司 2024-08-20 CN claimed
CN-113423782-B Method for preparing flame retardant auxiliary and flame retardant resin composition comprising the flame retardant auxiliary prepared thereby 株式会社LG化学 2024-07-12 CN claimed
US-20240198582-A1 HYBRID RESIN COMPOSITION FOR THE 3D-PRINTING OF OBJECTS CUBICURE GMBH (AT) 2024-06-20 US claimed
CN-114671902-B Method for producing modified-methyl tributyl ketoximino silane by fixed bed 浙江锦华新材料股份有限公司 2024-05-17 CN claimed
CN-113998931-A Preparation method of kaolin polymer-based regenerated EPS (expandable polystyrene) building exterior wall thermal insulation material 惠州市广润环保科技有限公司 2022-02-01 CN claimed
US-8143362-B2 Composition containing unsaturated silicone compounds, dental materials containing them and use thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-03-27 US claimed
US-20100331444-A1 COMPOSITION CONTAINING UNSATURATED SILICONE COMPOUNDS, DENTAL MATERIALS CONTAINING THEM AND USE THEREOF 3M ESPE AG (A WHOLLY-OWNED SUBSIDUARY OF 3M COMPANY) 2010-12-30 US claimed
US-7807730-B2 Composition containing unsaturated silicone compounds, dental materials containing them and use thereof 3M ESPE AG (DE) 2010-10-05 US claimed
EP-1448612-B1 VINYLAROMATIC POLYMERS WITH IMPROVED FLAME RESISTANCE POLIMERI EUROPA SPA (IT) 2008-12-31 EP claimed
EP-0032993-B2 FIREPROOFED STYRENE POLYMERS BASF Aktiengesellschaft (DE) 1987-09-23 EP claimed
EP-0032993-B1 FIREPROOFED STYRENE POLYMERS BASF Aktiengesellschaft (DE) 1983-09-21 EP claimed
US-4293656-A Flame retardant polystyrene BASF AKTIENGESELLSCHAFT (DE) 1981-10-06 US claimed
EP-0032993-A2 Fireproofed styrene polymers BASF Aktiengesellschaft (DE) 1981-08-05 EP claimed
US-4027063-A CIRCUIT BOARDS, METH-ACRYLOYLOXY-TERMINATED BUTADIENE RESIN, HALOGEN CONTAINING MONOMER AND UNSATURATED ANHYDRIDE SONY CORPORATION (JA) 1977-05-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100331444-A1 COMPOSITION CONTAINING UNSATURATED SILICONE COMPOUNDS, DENTAL MATERIALS CONTAINING THEM AND USE THEREOF SMCHD1, CAD, ESD ALDH1A1 1550/4885LMNA 664/4885SMN1; SMN2 1710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.