Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 7/20 | 0.43 |
| ▸ | GBA1 | P04062 | 3/20 | 0.41 |
| ▸ | PPP5C | P53041 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18573913 | 1.00 | THRB (0.45) | THRBLMNAMAPTBCHEGBA1 | |
| SCHEMBL8716781 | 0.95 | GBA1 (0.46) | THRBLMNAMAPTBCHEGBA1 | |
| SCHEMBL18107569 | 0.93 | GBA1 (0.49) | THRBLMNAMAPTBCHEGBA1 | |
| SCHEMBL18108272 | 0.93 | GBA1 (0.49) | THRBLMNAMAPTBCHEGBA1 | |
| SCHEMBL18107971 | 0.93 | GBA1 (0.49) | THRBLMNAMAPTBCHEGBA1 | |
| SCHEMBL1896686 | 0.93 | GBA1 (0.49) | THRBLMNAMAPTBCHEGBA1 | |
| SCHEMBL18107572 | 0.93 | GBA1 (0.49) | THRBLMNAMAPTBCHEGBA1 | |
| SCHEMBL18107973 | 0.93 | GBA1 (0.49) | THRBLMNAMAPTBCHEGBA1 | |
| SCHEMBL18118480 | 0.93 | GBA1 (0.49) | THRBLMNAMAPTBCHEGBA1 | |
| SCHEMBL18107970 | 0.93 | GBA1 (0.49) | THRBLMNAMAPTBCHEGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070020200-A1 | Therapeutic compositions and methods of use thereof | HODOSH MILTON | 2007-01-25 | — | — | US | claimed |
| US-7115252-B2 | Therapeutic compositions and methods of use thereof | HODOSH MILTON | 2006-10-03 | — | — | US | claimed |
| US-20030003163-A1 | Therapeutic compositions and methods of use thereof | HODOSH MILTON (US) | 2003-01-02 | — | — | US | claimed |
| EP-0186276-B1 | ORAL HYGIENE COMPOSITION | ICI AMERICAS INC. (US) | 1990-11-22 | — | — | EP | claimed |
| US-4632937-A | MONG-AND DIALKYL ETHERS OF DIANHYDROHEXITOLS | ICI AMERICAS (US) | 1986-12-30 | — | — | US | claimed |
| US-4627979-A | MONOALKYL AND DIALKYL ETHERS OF DIANHYDROHEXITOLS | ICI AMERICAS INC. (US) | 1986-12-09 | — | — | US | claimed |
| US-4627975-A | MONO AND DIALKYLETHERS OF DIANHYDROHEXITOLS | ICI AMERICAS INC. (US) | 1986-12-09 | — | — | US | claimed |
| US-4627974-A | CHEWING GUM WITH MONOALKYL AND DIALKYL DIANHYDROHEXITOLS | ICI AMERICAS INC. (US) | 1986-12-09 | — | — | US | claimed |
| US-4627976-A | Dentifrice formulation and method of treating teeth, mouth and throat therewith to reduce plaque accumulation and irritation | ICI AMERICAS INC. (US) | 1986-12-09 | — | — | US | claimed |
| US-4627980-A | MONOALKYL AND DIALKYL ETHERS OF DIANHYDROHEXITOLS | ICI AMERICAS INC. (US) | 1986-12-09 | — | — | US | claimed |
| US-4627978-A | Tooth drop dentifrice formulation and method of treating teeth, mouth and throat therewith to reduce plaque accumulation and irritation | ICI AMERICAS INC. (US) | 1986-12-09 | — | — | US | claimed |
| US-4610871-A | Dentifrice formulation and method of treating teeth, mouth and throat therewith to reduce plaque accumulation and irritation | ICI AMERICAS INC. (US) | 1986-09-09 | — | — | US | claimed |
| US-4610872-A | Dentifrice formulation and method of treating teeth, mouth and throat therewith to reduce plaque accumulation and irritation | ICI AMERICAS INC. (US) | 1986-09-09 | — | — | US | claimed |
| EP-0186276-A2 | Oral hygiene composition | ICI AMERICAS INC. (US) | 1986-07-02 | — | — | EP | claimed |
| US-4585649-A | MONO- AND DIALKYL ETHERS OF DIANHYDROHEXITOLS | ICI AMERICAS INC. (US) | 1986-04-29 | — | — | US | claimed |
| EP-4376796-A1 | TRANSPARENT AQUEOUS PERFUME COMPOSITION | V. Mane Fils (FR) | 2024-06-05 | — | — | EP | disclosed |
| CN-118043023-A | Transparent aqueous perfume composition | 威·曼父子有限公司 | 2024-05-14 | — | — | CN | disclosed |
| US-4610871-A | Dentifrice formulation and method of treating teeth, mouth and throat therewith to reduce plaque accumulation and irritation | ICI AMERICAS INC. (US) | 1986-09-09 | — | — | US | disclosed |
| EP-0186276-A2 | Oral hygiene composition | ICI AMERICAS INC. (US) | 1986-07-02 | — | — | EP | disclosed |
| US-4585649-A | MONO- AND DIALKYL ETHERS OF DIANHYDROHEXITOLS | ICI AMERICAS INC. (US) | 1986-04-29 | — | — | US | disclosed |