SCHEMBL19002944

SCHEMBL19002944

ClCc1cc(CCl)cc(-c2cc(CCl)cc(CCl)c2)c1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11317816 0.97
SCHEMBL1050358 0.89 CA1 (0.33) TSHR
SCHEMBL5486041 0.84 GRIN2D (0.47) TSHR
SCHEMBL11308746 0.80
SCHEMBL30539351 0.76 ACHE (0.50) TSHR
SCHEMBL11743237 0.76 TSHR (0.44) TSHR
SCHEMBL14590080 0.76 AGXT (0.45) TSHR
SCHEMBL17407558 0.73 IDO1 (0.39) TSHR
SCHEMBL18142147 0.73
SCHEMBL608037 0.73 PTGS2 (0.39) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3507269-B1 STABLE HYDROFORMYLATION CATALYST FOR PREPARATION OF HIGH N/ISO RATIO ALDEHYDE PRODUCT EASTMAN CHEM CO (US) 2020-09-23 EP disclosed
EP-3507269-A1 STABLE HYDROFORMYLATION CATALYST FOR PREPARATION OF HIGH N/ISO RATIO ALDEHYDE PRODUCT Eastman Chemical Company (US) 2019-07-10 EP disclosed
WO-2018044827-A1 STABLE HYDROFORMYLATION CATALYST FOR PREPARATION OF HIGH N/ISO RATIO ALDEHYDE PRODUCT EASTMAN CHEMICAL COMPANY (US) 2018-03-08 WO disclosed
US-9687837-B1 Stable hydroformylation catalyst for preparation of high N/Iso ratio aldehyde product EASTMAN CHEMICAL COMPANY (US) 2017-06-27 US disclosed