Toluene

Toluene

SCHEMBL190031

C1CCOC1.Cc1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.58
ACHE P22303 3/20 0.58
TSHR P16473 1/20 0.58
ALOX12 P18054 1/20 0.58
ALDH1A1 P00352 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.39
CRHBP P24387 2/20 0.39
CRHR2 Q13324 2/20 0.39
HTT P42858 1/20 0.39
ORAI1 Q96D31 1/20 0.37
ORAI2 Q96SN7 1/20 0.37
ORAI3 Q9BRQ5 1/20 0.37
TRPV6 Q9H1D0 1/20 0.37
HPGD P15428 2/20 0.37
POLB P06746 2/20 0.35
NPC1 O15118 1/20 0.35
NFKB1 P19838 1/20 0.35
RAB9A P51151 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL27542416 1.00 LMNA (0.58) LMNAACHETSHRALOX12ALDH1A1
Toluene SCHEMBL9640890 1.00 LMNA (0.58) LMNAACHETSHRALOX12ALDH1A1
Toluene SCHEMBL9640920 1.00 LMNA (0.58) LMNAACHETSHRALOX12ALDH1A1
Toluene SCHEMBL28199131 0.97 LMNA (0.55) LMNAACHETSHRALOX12ALDH1A1
Toluene SCHEMBL28340976 0.97 LMNA (0.55) LMNAACHETSHRALOX12ALDH1A1
Toluene SCHEMBL7754119 0.97 LMNA (0.55) LMNAACHETSHRALOX12ALDH1A1
Toluene SCHEMBL27620801 0.97 LMNA (0.55) LMNAACHETSHRALOX12ALDH1A1
Toluene SCHEMBL10611917 0.97 LMNA (0.55) LMNAACHETSHRALOX12ALDH1A1
Toluene SCHEMBL7754116 0.97 LMNA (0.55) LMNAACHETSHRALOX12ALDH1A1
Toluene SCHEMBL5070511 0.97 LMNA (0.55) LMNAACHETSHRALOX12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 976 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116969996-B Ethylene selective trimerization catalytic ligand, preparation method, catalytic system and application thereof 卫星化学股份有限公司 2024-05-03 CN claimed
CN-114797989-B Supported catalyst and preparation method and application thereof 卫星化学股份有限公司 2024-02-23 CN claimed
CN-117510482-A AIE probe for targeting cell membrane and preparation method and application thereof 武汉大学 2024-02-06 CN claimed
CN-116969996-A Ethylene selective trimerization catalytic ligand, preparation method, catalytic system and application thereof 卫星化学股份有限公司 2023-10-31 CN claimed
CN-116854626-A Preparation method of 2-vinyl pyridine 河南省科学院高新技术研究中心 2023-10-10 CN claimed
CN-115215795-B Synthesis method of flonicamid 帕潘纳(北京)科技有限公司 2023-07-25 CN claimed
CN-116136490-A Method for measuring electron spin life of semiconductor colloid nano material based on doping method 中国科学院大连化学物理研究所 2023-05-19 CN claimed
CN-113466366-B Method for measuring content of di-tert-butyl peroxide in polypropylene special material for melt-blowing 江苏省纺织产品质量监督检验研究院 2023-04-07 CN claimed
CN-115785122-A Indole derivative piperidine compound and synthetic method thereof 江苏师范大学 2023-03-14 CN claimed
CN-111763225-B Preparation method of anhydrous tris (pentafluorophenyl) borane 卫星化学股份有限公司 2023-02-10 CN claimed
US-20010003726-A1 INITIATION SYSTEM COMPRISING AN AMINO ALCOHOLATE LIGAND FOR ANIONIC COPOLYMERIZATION OF (METH)ACRYLIC MONOMERS AND PROCESS USING SAME ELF ATOCHEM S.A. (FR) 2001-06-14 US claimed
CN-1276781-A Process for enhancing optical purity of 2R-[1-hydroxy-1-trifluoromethyl-3-cyclopropylpropyn-2-yl]-4-chloroaniline MERCK & CO INC (US) 2000-12-13 CN claimed
EP-1017666-A1 PROCESS FOR ENHANCING THE OPTICAL PURITY OF 2R- 1-HYDROXY- 1-TRIFLUOROMETHYL- 3-CYCLOPROPYLPROPYN-2YL] -4-CHLOROANILINE Merck & Co., Inc. (US) 2000-07-12 EP claimed
US-5952528-A ADDING AN ACID SOLUTION TO A SOLUTION OF AMINO ALCOHOL IN AN ORGANIC SOLVENT TO FORM SLURRY OF ACID ADDITION SALT, CONCENTRATING THE SLURRY, FLUSHING WITH SOLVENT, AGING, FILTERING, WASHING AND DRYING MERCK & CO., INC. (US) 1999-09-14 US claimed
WO-1999011600-A1 PROCESS FOR ENHANCING THE OPTICAL PURITY OF 2R-[1-HYDROXY- 1-TRIFLUOROMETHYL- 3-CYCLOPROPYLPROPYN-2YL] -4-CHLOROANILINE MERCK & CO., INC. (US) 1999-03-11 WO claimed
US-5663334-A CYTOKINE INHIBITORS FORMED BY REACTION OF IMINE WITH SULFUR SUBSTITUTED NITRILE SMITHKLINE BEECHAM CORPORATION (US) 1997-09-02 US claimed
US-5380849-A Process for optically pure decahydroisoqiunolines MERCK & CO., INC. (US) 1995-01-10 US claimed
EP-0596108-A1 PROCESS FOR PRODUCING ALDEHYDE BY OXIDIZING PRIMARY ALCOHOL Japan Tobacco Inc. (JP) 1994-05-11 EP claimed
US-4422982-A Method for preparation of N-phosphonomethylglycine STAUFFER CHEMICAL COMPANY (US) 1983-12-27 US claimed
US-4192720-A Electrodeposition process for forming amorphous silicon EXXON RESEARCH & ENGINEERING CO. (US) 1980-03-11 US claimed