Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 2/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.36 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.36 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL27277002 | 1.00 | LMNA (0.55) | LMNAACHETSHRALOX12ALDH1A1 | |
| Toluene SCHEMBL10611917 | 1.00 | LMNA (0.55) | LMNAACHETSHRALOX12ALDH1A1 | |
| Toluene SCHEMBL7754116 | 1.00 | LMNA (0.55) | LMNAACHETSHRALOX12ALDH1A1 | |
| Toluene SCHEMBL27279839 | 0.98 | LMNA (0.52) | LMNAACHETSHRALOX12ALDH1A1 | |
| Toluene SCHEMBL9640920 | 0.97 | LMNA (0.58) | LMNAACHETSHRALOX12ALDH1A1 | |
| Toluene SCHEMBL27542416 | 0.97 | LMNA (0.58) | LMNAACHETSHRALOX12ALDH1A1 | |
| Toluene SCHEMBL9640890 | 0.97 | LMNA (0.58) | LMNAACHETSHRALOX12ALDH1A1 | |
| Toluene SCHEMBL190031 | 0.97 | LMNA (0.58) | LMNAACHETSHRALOX12ALDH1A1 | |
| Toluene SCHEMBL7754119 | 0.95 | LMNA (0.55) | LMNAACHETSHRALOX12ALDH1A1 | |
| Toluene SCHEMBL28323002 | 0.95 | LMNA (0.55) | LMNAACHETSHRALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023219521-A1 | NEW 2-(DIETHYLAMINO)-4,6-DIPHENYLBENZENE-1,3-CARBONITRILE DERIVATIVES, METHOD OF THEIR PRODUCTION, THEIR USE AND NEW PHOTOINITIATING SYSTEMS FOR PHOTOINITIATED CATIONIC, RADICAL, THIOL-ENE AND HYBRID POLYMERIZATION | Politechnika Krakowska im. Tadeusza Kościuszki (PL) | 2023-11-16 | — | — | WO | claimed |
| CN-111620850-A | Preparation method of 1- (3-chloropyridine-2-yl) -3-bromo-1H-pyrazole-5-formic ether | 江苏七洲绿色化工股份有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-117924285-A | Pharmaceutically effective compounds for selectively inhibiting myosin 2 isoforms | 普林特商业服务有限公司 | 2024-04-26 | — | — | CN | disclosed |
| WO-2023219521-A1 | NEW 2-(DIETHYLAMINO)-4,6-DIPHENYLBENZENE-1,3-CARBONITRILE DERIVATIVES, METHOD OF THEIR PRODUCTION, THEIR USE AND NEW PHOTOINITIATING SYSTEMS FOR PHOTOINITIATED CATIONIC, RADICAL, THIOL-ENE AND HYBRID POLYMERIZATION | Politechnika Krakowska im. Tadeusza Kościuszki (PL) | 2023-11-16 | — | — | WO | disclosed |
| CN-115279370-A | Compounds for targeted degradation of BRD9 | C4医药公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-111362966-B | Bicyclic heterocyclic derivatives as IRAK4 inhibitors | 奥列基因发现技术有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-111620850-B | Preparation method of 1- (3-chloropyridine-2-yl) -3-bromo-1H-pyrazole-5-formic ether | 江苏七洲绿色化工股份有限公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-107922407-B | Respiratory syncytial virus inhibitors | 勃林格殷格翰国际有限公司 | 2020-09-25 | — | — | CN | disclosed |
| CN-111620850-A | Preparation method of 1- (3-chloropyridine-2-yl) -3-bromo-1H-pyrazole-5-formic ether | 江苏七洲绿色化工股份有限公司 | 2020-09-04 | — | — | CN | disclosed |
| CN-111448205-A | Vaccine against klebsiella pneumoniae | 瓦希隆股份公司 | 2020-07-24 | — | — | CN | disclosed |
| CN-111362966-A | Bicyclic heterocyclic derivatives as IRAK4 inhibitors | 奥列基因发现技术有限公司 | 2020-07-03 | — | — | CN | disclosed |
| WO-1983004021-A1 | 2,3,4-TRINOR-1,5-INTER-M-PHENYLENE-PROSTACYCLINE-I2 ANALOGUES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1983-11-24 | — | — | WO | disclosed |
| US-4410527-A | ANTIULCER AGENTS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-10-18 | — | — | US | disclosed |
| US-4382031-A | Intermediates for the preparation of biotin | HOFFMANN-LA ROCHE INC. (US) | 1983-05-03 | — | — | US | disclosed |
| US-4320056-A | Certain thia-diazatricyclo[3,3,3,08,11 ]tridecanes, and their preparation | HOFFMANN-LA ROCHE INC. (US) | 1982-03-16 | — | — | US | disclosed |
| US-4284557-A | Intermediate racemates for the preparation of biotin and a process for their preparation | HOFFMANN-LA ROCHE INC. (US) | 1981-08-18 | — | — | US | disclosed |
| US-4255330-A | CYCLIZATION IN THE PRESENCE OF A STRONG BASE AND A METAL COMPLEX | MERCK & CO., INC. (US) | 1981-03-10 | — | — | US | disclosed |
| US-4247704-A | Hexahydro thieno imadazole intermediates for the synthesis of biotin | HOFFMANN-LA ROCHE INC. (US) | 1981-01-27 | — | — | US | disclosed |
| EP-0019788-A2 | Novel process for the manufacture of thiophene derivatives suited for the manufacture of biotin, process for the manufacture of biotin and novel intermediates in this process | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-12-10 | — | — | EP | disclosed |
| US-4123555-A | Sulfide compounds and methods and compositions for treating depression | BURROUGHS WELLCOME CO. (US) | 1978-10-31 | — | — | US | disclosed |