Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.51 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003344 | 0.84 | KMT2A (0.49) | TP53APPKMT2AMAPTMEN1 | |
| SCHEMBL19003339 | 0.82 | MAPT (0.57) | APPKMT2AMAPTMEN1PSMD14 | |
| SCHEMBL19003282 | 0.81 | TP53 (0.50) | TP53KMT2AMAPTMEN1HPGD | |
| SCHEMBL19003343 | 0.81 | MAPT (0.46) | TP53APPKMT2AMAPTMEN1 | |
| SCHEMBL14730414 | 0.79 | MAPT (0.74) | APPKMT2AMAPTMEN1HPGD | |
| SCHEMBL15859151 | 0.79 | MAPT (0.74) | APPKMT2AMAPTMEN1HPGD | |
| SCHEMBL15859149 | 0.79 | MAPT (0.74) | APPKMT2AMAPTMEN1HPGD | |
| SCHEMBL19003275 | 0.77 | KMT2A (0.48) | TP53KMT2AMAPTMEN1HPGD | |
| SCHEMBL12372827 | 0.76 | NQO2 (0.77) | TP53KMT2AMAPTMEN1HPGD | |
| SCHEMBL19003466 | 0.75 | NQO2 (0.56) | TP53KMT2AMAPTMEN1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |