Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.48 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.48 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003272 | 0.84 | MAPT (0.56) | MAPTKMT2ALMNAMAPK1MEN1 | |
| SCHEMBL11936937 | 0.83 | MAPT (0.57) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL19003340 | 0.82 | TP53 (0.52) | MAPTKMT2ALMNAMAPK1MEN1 | |
| SCHEMBL19003267 | 0.80 | MAPT (0.52) | MAPTKMT2ALMNAMAPK1MEN1 | |
| SCHEMBL19003304 | 0.79 | ABL1 (0.58) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL19003343 | 0.77 | MAPT (0.46) | MAPTKMT2ALMNAMAPK1MEN1 | |
| SCHEMBL19003344 | 0.76 | KMT2A (0.49) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL11936936 | 0.74 | MAPT (0.60) | MAPTKMT2ALMNAMAPK1MEN1 | |
| SCHEMBL11936935 | 0.73 | MAPT (0.58) | MAPTKMT2ALMNAMAPK1MEN1 | |
| SCHEMBL15859149 | 0.73 | MAPT (0.74) | MAPTKMT2ALMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |