Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003268 | 0.84 | MAPT (0.47) | KMT2AMEN1MAPTTHRBPKM | |
| SCHEMBL19003340 | 0.84 | TP53 (0.52) | KMT2AMEN1MAPTTHRBPKM | |
| SCHEMBL19003269 | 0.81 | KMT2A (0.49) | KMT2AMEN1MAPTTHRBPKM | |
| SCHEMBL14730331 | 0.79 | MAPT (0.59) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL15859167 | 0.79 | MAPT (0.59) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL19003461 | 0.79 | EGFR (0.54) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL15859194 | 0.77 | MAPT (0.56) | MAPTALDH1A1KDM4ETP53POLB | |
| SCHEMBL15859196 | 0.77 | MAPT (0.56) | MAPTALDH1A1KDM4ETP53POLB | |
| SCHEMBL19003339 | 0.76 | MAPT (0.57) | KMT2AMEN1MAPTPKMALDH1A1 | |
| SCHEMBL19003343 | 0.74 | MAPT (0.46) | KMT2AMEN1MAPTTHRBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |