Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | DBH | P09172 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003399 | 0.82 | CA12 (0.56) | SNCAMAPTPTGS2KDM4ECA12 | |
| SCHEMBL19003635 | 0.81 | SNCA (0.50) | SNCAMAPTCA12CA1CA2 | |
| SCHEMBL11012667 | 0.81 | GAA (0.55) | SNCAMAPTKDM4EGAAPOLB | |
| SCHEMBL21845034 | 0.80 | HDAC1 (0.47) | SNCAMAPTPTGS2KDM4ECA12 | |
| SCHEMBL1758192 | 0.79 | CA12 (0.68) | SNCAMAPTPTGS2KDM4ECA12 | |
| SCHEMBL23484907 | 0.78 | HDAC1 (0.53) | SNCAMAPTPTGS2KDM4ECA12 | |
| SCHEMBL30023949 | 0.78 | CNR1 (0.49) | SNCAMAPTKDM4EGAAPOLB | |
| SCHEMBL29238849 | 0.78 | SIRT1 (0.61) | SNCAMAPTGAAPOLBHDAC6 | |
| SCHEMBL18993048 | 0.77 | CA12 (0.50) | MAPTPTGS2KDM4ECA12CA1 | |
| SCHEMBL1918258 | 0.77 | HDAC1 (0.61) | MAPTPTGS2KDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103961340-A | LSD1 inhibitors and application thereof | INST OCEANOLOGY CHINESE ACAD | 2014-08-06 | — | — | CN | claimed |
| US-11639325-B2 | Compositions of polyhydroxylated benzophenones and methods of treatment of neurodegenerative disorders | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-05-02 | — | — | US | disclosed |
| US-11639325-B2 | Compositions of polyhydroxylated benzophenones and methods of treatment of neurodegenerative disorders | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-05-02 | — | — | US | disclosed |
| CN-103961340-B | A kind of LSD1 inhibitor and its application | 南通中国科学院海洋研究所海洋科学与技术研究发展中心 | 2019-06-25 | — | — | CN | disclosed |
| WO-2017106861-A1 | COMPOSITIONS OF POLYHYDROXYLATED BENZOPHENONES AND METHODS OF TREATMENT OF NEURODEGENERATIVE DISORDERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-06-22 | — | — | WO | disclosed |
| CN-103961340-A | LSD1 inhibitors and application thereof | INST OCEANOLOGY CHINESE ACAD | 2014-08-06 | — | — | CN | disclosed |
| CN-103961340-A | LSD1 inhibitors and application thereof | INST OCEANOLOGY CHINESE ACAD | 2014-08-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11639325-B2 | Compositions of polyhydroxylated benzophenones and methods of treatment of neurodegenerative disorders | HDAC1, HDAC10, HDAC6 | SNCA 91/4885MAPT 27/4885PTGS2 3291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.