SCHEMBL1758192

SCHEMBL1758192

O=C(c1ccc(O)c(O)c1)c1ccc(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.68
CA1 P00915 4/20 0.68
CA2 P00918 4/20 0.68
CA7 P43166 4/20 0.68
CA9 Q16790 4/20 0.68
CA14 Q9ULX7 4/20 0.68
KDM4E B2RXH2 2/20 0.68
GAA P10253 2/20 0.68
MAPT P10636 2/20 0.68
POLB P06746 1/20 0.68
CA4 P22748 1/20 0.68
CA6 P23280 1/20 0.68
PTGS2 P35354 1/20 0.68
L3MBTL1 Q9Y468 1/20 0.68
SIRT1 Q96EB6 1/20 0.67
HDAC6 Q9UBN7 1/20 0.60
DBH P09172 1/20 0.58
RECQL P46063 1/20 0.58
XDH P47989 1/20 0.58
TOP1 P11387 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10589365 0.91 FASN (0.62) CA12CA1CA2CA7CA9
SCHEMBL5476111 0.91 MAPT (0.68) CA12CA1CA2CA7CA9
SCHEMBL8861226 0.89 SIRT1 (0.56) CA12CA1CA2CA7CA9
SCHEMBL142204 0.89 L3MBTL1 (0.64) CA12CA1CA2CA7CA9
SCHEMBL31257839 0.89 L3MBTL1 (0.64) CA12CA1CA2CA7CA9
SCHEMBL6746043 0.87 MAPK1 (0.63) CA12CA1CA2CA7CA9
SCHEMBL6742077 0.87 SIRT1 (0.59) CA12CA1CA2CA7CA9
SCHEMBL6839571 0.87 ALDH1A1 (0.67) CA12CA1CA2CA7CA9
SCHEMBL30006432 0.87 MAPK1 (0.63) CA12CA1CA2CA7CA9
SCHEMBL6744685 0.87 SIRT1 (0.59) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108727399-B A kind of benzo dioxane indole derivatives and its preparation method and application 福州大学 2019-06-07 CN claimed
CN-108602837-A With the compound and its salt for inhibiting platelet aggregation effect and include its composition for preventing or treating thrombotic diseases 新丰制药株式会社 2018-09-28 CN claimed
EP-0692733-B1 Direct thermal recording process AGFA GEVAERT NV (BE) 1998-02-04 EP claimed
US-5582953-A IMAGING LAYER CONTAINING SILVER SALTS AND ORGANIC DIHYDROXYL-CONTAINING REDUCING AGENT THEREFOR AGFA-GEVAERT N.V. (BE) 1996-12-10 US claimed
EP-0395346-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-11-27 EP claimed
EP-0692733-A2 Direct thermal recording process AGFA-GEVAERT N.V. (BE) 1996-01-17 EP claimed
US-5254432-A Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-10-19 US claimed
US-5019612-A Heat Resistance, Oxidation Resistance, Photostability, Polymers CIBA-GEIGY CORPORATION (US) 1991-05-28 US claimed
EP-0395346-A2 Photosensitive composition Fuji Photo Film Co., Ltd. (JP) 1990-10-31 EP claimed
US-4015017-A Certain biphenyl derivatives used to treat disorders caused by increased capillary permeability LABORATOIRES PHARMASCIENCE (FR) 1977-03-29 US claimed
US-12044969-B2 Resist underlayer film-forming composition NISSAN CHEMICAL CORPORATION (JP) 2024-07-23 US disclosed
US-12044969-B2 Resist underlayer film-forming composition NISSAN CHEMICAL CORPORATION (JP) 2024-07-23 US disclosed
US-11639325-B2 Compositions of polyhydroxylated benzophenones and methods of treatment of neurodegenerative disorders MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-05-02 US disclosed
US-11639325-B2 Compositions of polyhydroxylated benzophenones and methods of treatment of neurodegenerative disorders MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-05-02 US disclosed
CN-113795435-B Soluble package of pre-measured powdered hair bleach 莱雅公司 2023-04-25 CN disclosed
US-4732836-A SOLUTION STABILITY PHENOLIC COMPOUNDS CONDENSED WITH QUINONES HOECHST CELANESE CORPORATION (US) 1988-03-22 US disclosed
EP-0244763-A2 Positive-working photosensitive composition and photosensitive recording material prepared therefrom HOECHST CELANESE CORPORATION (US) 1987-11-11 EP disclosed
EP-0244762-A2 Photosensitive positive composition and photosensitive registration material prepared therefrom HOECHST CELANESE CORPORATION (US) 1987-11-11 EP disclosed
EP-0243964-A2 Photosensitive positive composition and photosensitive registration material prepared therefrom HOECHST CELANESE CORPORATION (US) 1987-11-04 EP disclosed
US-4015017-A Certain biphenyl derivatives used to treat disorders caused by increased capillary permeability LABORATOIRES PHARMASCIENCE (FR) 1977-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11639325-B2 Compositions of polyhydroxylated benzophenones and methods of treatment of neurodegenerative disorders HDAC1, HDAC10, HDAC6 CA12 3937/4885CA1 1764/4885CA2 4324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.