Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.69 |
| ▸ | RAB9A | P51151 | 6/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.69 |
| ▸ | MAOB | P27338 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | HPGD | P15428 | 6/20 | 0.66 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.66 |
| ▸ | GAPDH | P04406 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.66 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12387899 | 0.84 | ALDH1A1 (0.69) | ALDH1A1RAB9AKDM4EMAOBSMN1; SMN2 | |
| SCHEMBL13757027 | 0.83 | ALDH1A1 (0.61) | ALDH1A1RAB9AKDM4EMAOBSMN1; SMN2 | |
| SCHEMBL13757025 | 0.83 | ALDH1A1 (0.75) | ALDH1A1RAB9AKDM4EMAOBSMN1; SMN2 | |
| SCHEMBL14389070 | 0.83 | MAOB (0.75) | ALDH1A1RAB9AKDM4EMAOBSMN1; SMN2 | |
| SCHEMBL13757026 | 0.83 | ALDH1A1 (0.67) | ALDH1A1RAB9AKDM4EMAOBSMN1; SMN2 | |
| SCHEMBL8934577 | 0.83 | ALDH1A1 (0.68) | ALDH1A1RAB9AKDM4EMAOBSMN1; SMN2 | |
| SCHEMBL177366 | 0.82 | RAB9A (1.00) | ALDH1A1RAB9AKDM4EMAOBSMN1; SMN2 | |
| SCHEMBL30356319 | 0.82 | RAB9A (1.00) | ALDH1A1RAB9AKDM4EMAOBSMN1; SMN2 | |
| SCHEMBL4992894 | 0.81 | MAOB (0.55) | KDM4EMAOBGAPDHMAPTMEN1 | |
| SCHEMBL4987026 | 0.81 | MAOB (0.55) | ALDH1A1RAB9AKDM4EMAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11382991-B2 | Molecular probes for imaging of myelin | CASE WESTERN RESERVE UNIVERSITY (US) | 2022-07-12 | — | — | US | disclosed |
| EP-2910945-B1 | Molecular probes for imaging of myelin | UNIV CASE WESTERN RESERVE (US) | 2018-07-18 | — | — | EP | disclosed |
| US-9987379-B2 | Molecular probes for imaging of myelin | CASE WESTERN RESERVE UNIVERSITY (US) | 2018-06-05 | — | — | US | disclosed |
| US-20170176469-A1 | Molecular Probes for Detecting Lipids | CASE WESTERN UNIVERSITY | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11382991-B2 | Molecular probes for imaging of myelin | MAG, MYT1, PMP22 | ALDH1A1 3088/4885RAB9A 2852/4885KDM4E 2693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.