Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.75 |
| ▸ | MAPT | P10636 | 6/20 | 0.75 |
| ▸ | RAB9A | P51151 | 5/20 | 0.75 |
| ▸ | MEN1 | O00255 | 5/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.75 |
| ▸ | NPC1 | O15118 | 4/20 | 0.75 |
| ▸ | GAA | P10253 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18985269 | 0.83 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL18985214 | 0.83 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL18985268 | 0.83 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL18985212 | 0.83 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL19003256 | 0.82 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL19003468 | 0.81 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL27752098 | 0.78 | RAB9A (1.00) | ALDH1A1SMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL31162549 | 0.77 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2MAPTKMT2AGAA | |
| SCHEMBL14096457 | 0.74 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MAPTRAB9AMEN1 | |
| SCHEMBL2069934 | 0.74 | PKM (1.00) | ALDH1A1SMN1; SMN2MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |