Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PORCN | Q9H237 | 8/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | ADH5 | P11766 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003466 | 0.79 | NQO2 (0.56) | RAB9AALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL18985528 | 0.79 | NQO2 (0.56) | RAB9AALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19003474 | 0.79 | MEN1 (0.47) | PORCNCYP3A4CYP2D6RAB9AALDH1A1 | |
| SCHEMBL19003465 | 0.79 | MAPT (0.65) | PORCNRAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL19003299 | 0.78 | MAPT (0.52) | RAB9AALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19003302 | 0.78 | HSD17B1 (0.48) | RAB9AALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19003304 | 0.77 | ABL1 (0.58) | RAB9AALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19003303 | 0.77 | MAOB (0.52) | RAB9AALDH1A1MEN1KMT2AHSD17B1 | |
| SCHEMBL18985199 | 0.76 | NAMPT (0.48) | RAB9AALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19003456 | 0.74 | MAPT (0.48) | RAB9AALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |