Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PORCN | Q9H237 | 8/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | ADH5 | P11766 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003467 | 0.79 | PORCN (0.54) | MEN1ALOX15TSHRKMT2APORCN | |
| SCHEMBL6660795 | 0.67 | MEN1 (1.00) | MEN1ALOX15TSHRKMT2APORCN | |
| SCHEMBL27958208 | 0.67 | CYP11B1 (0.54) | MEN1ALOX15TSHRKMT2APORCN | |
| Water SCHEMBL6337291 | 0.66 | MEN1 (0.96) | MEN1ALOX15TSHRKMT2APORCN | |
| SCHEMBL28484940 | 0.65 | CYP3A4 (0.71) | MEN1ALOX15TSHRKMT2APORCN | |
| SCHEMBL18746528 | 0.64 | CYP3A4 (0.65) | MEN1ALOX15TSHRKMT2ACYP3A4 | |
| SCHEMBL451 | 0.64 | CYP3A4 (1.00) | MEN1ALOX15TSHRKMT2ACYP3A4 | |
| SCHEMBL24782873 | 0.63 | LMNA (0.55) | MEN1ALOX15TSHRKMT2APORCN | |
| SCHEMBL8392726 | 0.63 | CYP3A4 (0.69) | MEN1ALOX15TSHRKMT2ACYP3A4 | |
| SCHEMBL2604923 | 0.63 | CYP3A4 (0.69) | MEN1ALOX15TSHRKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |