SCHEMBL19003499

SCHEMBL19003499

CCCCC(CCCC)c1nnn[nH]1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20000893 0.96
SCHEMBL20824834 0.94 OPRM1 (0.32)
SCHEMBL18551463 0.92 LMNA (0.33) DNM1
SCHEMBL18649822 0.92 LMNA (0.33) DNM1
SCHEMBL19558131 0.92 LMNA (0.33) DNM1
SCHEMBL5641783 0.89 ALDH1A1 (0.35)
SCHEMBL6050181 0.88
SCHEMBL18596679 0.87 KDM4E (0.30)
SCHEMBL5641699 0.86
SCHEMBL20915188 0.85 NR1I2 (0.36) DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023170024-A1 CAMK2 MODULATORS AND THEIR USE IN MEDICINE UNIVERSITY OF COPENHAGEN (DK) 2023-09-14 WO disclosed
EP-2938344-B1 PIPERAZINE-SUBSTITUTED [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES MERCK SHARP & DOHME (US) 2017-06-21 EP disclosed